Evidence map›Paper›PMID 39477492›Full record

ArticleJournal of nuclear medicine : official publication, Society of Nuclear Medicine2024

Feasibility, Tolerability, and Preliminary Clinical Response of Fractionated Radiopharmaceutical Therapy with

Andreas Helisch, Clemens Kratochwil, Christian Kleist, Susanne Krämer, Juan Jose Rosales Castillo, Katharina Dendl, Hendrik Rathke, Isabelle von Goetze, Mathias Schreckenberger, Dirk Jäger and 5 more

Abstract read
In one paragraph

Article in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Comparison of [European journal of nuclear medicine and molecular imaging · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Andreas HelischDepartment of Nuclear Medicine, University Medical Center, Mainz, Germany.
Clemens KratochwilDepartment of Nuclear Medicine, Heidelberg University Hospital, Heidelberg, Germany.
Christian KleistDepartment of Nuclear Medicine, Heidelberg University Hospital, Heidelberg, Germany.
Susanne KrämerDepartment of Nuclear Medicine, Heidelberg University Hospital, Heidelberg, Germany.
Juan Jose Rosales CastilloDepartment of Nuclear Medicine, University Clinic of Navarra, Pamplona, Spain.
Katharina DendlDepartment of Nuclear Medicine, Heidelberg University Hospital, Heidelberg, Germany.
Hendrik RathkeDepartment of Nuclear Medicine, Heidelberg University Hospital, Heidelberg, Germany.
Isabelle von GoetzeDepartment of Nuclear Medicine, University Medical Center, Mainz, Germany.
Mathias SchreckenbergerDepartment of Nuclear Medicine, University Medical Center, Mainz, Germany.
Dirk JägerDepartment of Medical Oncology, Heidelberg University Hospital, National Center for Tumor Diseases, Heidelberg, Germany.
Thomas LindnerDepartment of Nuclear Medicine, Heidelberg University Hospital, Heidelberg, Germany.
Walter MierDepartment of Nuclear Medicine, Heidelberg University Hospital, Heidelberg, Germany.
Frederik GieselDepartment of Nuclear Medicine, Heidelberg University Hospital, Heidelberg, Germany.
Uwe HaberkornDepartment of Nuclear Medicine, Heidelberg University Hospital, Heidelberg, Germany.
Manuel RöhrichDepartment of Nuclear Medicine, University Medical Center, Mainz, Germany; manuel.roehrich@unimedizin-mainz.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Radiopharmaceutical therapies (RPTs) based on fibroblast activation protein (FAP) and FAP inhibitors (FAPIs) are a new option for progressive metastatic cancer in patients pretreated multiple times. To date, published in-human data refer to initial experiences with β-emitting

Indexed as

Feasibility StudiesNeoplasm MetastasisRadioisotopesRadiopharmaceuticalsAdolescentAdultAgedBismuthDisease ProgressionDose Fractionation, RadiationEndopeptidasesFemaleFibroblast Activation Protein AlphaHumansMaleMembrane ProteinsBismuthBismuth-213EndopeptidasesFibroblast Activation Protein AlphaMembrane ProteinsRadioisotopesRadiopharmaceuticalsbismuthFAPIradiopharmaceutical therapytargeted therapyα-therapy

Identifiers

PMID39477492
PMCPMC11619590

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.