Evidence map›Paper›PMID 39477281›Full record

ArticleBMJ open2024

Association between physical activity and immunosuppressive medication adherence among renal transplant recipients: a case-control study.

Pengpeng Zhang, Xiaofei Fan, Linghui Xiang, Xiao Zhu, Dian Liu, Jia Liu

Abstract read
In one paragraph

Article in BMJ open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Pengpeng ZhangDepartment of Transplantation, The Third Xiangya Hospital of Central South University, Changsha, Hunan, China.
Xiaofei FanDepartment of Transplantation, The Third Xiangya Hospital of Central South University, Changsha, Hunan, China.
Linghui XiangDepartment of Epidemiology and Health Statistic, Central South University Xiangya School of Public Health, Changsha, Hunan, China.
Xiao ZhuDepartment of Transplantation, The Third Xiangya Hospital of Central South University, Changsha, Hunan, China.
Dian LiuDepartment of Graduate, The Third Xiangya Hospital of Central South University, Changsha, Hunan, China.
Jia LiuHealth Management Medical Center, The Third Xiangya Hospital of Central South University, Changsha, Hunan, China chucklejl@163.com.ORCID 0000-0003-2973-2507

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBehavioural interventions are closely associated with immunosuppressive medication (IM) adherence. We aimed to explore the relationship between physical activity and IM adherence among renal transplant patients (RTPs) to determine potential interventions to improve IM adherence.

designA case-control study.

settingSingle-centre study in Changsha, China.

participantsThe study population included 624 RTPs who were adherent to IM and 417 RTPs who were non-adherent to IM.

main outcome measuresSociodemographic characteristics of RTPs, IM adherence and the association between physical activity patterns or frequency and IM adherence.

resultsThe proportion of RTPs who were non-adherent to IM was 40.06%. Compared with RTPs non-adherent to IM, those who were adherent were older, more likely to be married, were evaluated closer to initial time of transplant, had shorter pretransplant waiting times and engaged in more physical activity. Multivariate logistic regression analysis showed that, in the pretransplant stage, only high-frequency aerobic physical activity was significantly associated with IM adherence. However, in the post-transplant stage, patients engaging in low-frequency aerobic physical activity, high-frequency resistance physical activity or high-frequency aerobic physical activity had 2.01, 2.96 and 2.67 times greater odds of being adherent to IM, respectively, compared with patients with no physical activity. RTPs without physical activity in the pretransplant stage were more likely to be adherent to IM if they engaged in post-transplant physical activity. RTPs engaging in low-frequency physical activity in the pretransplant stage may have better IM adherence if they engaged in post-transplant physical activity. RTPs engaging in high-frequency post-transplant physical activity were significantly associated with a greater likelihood of being adherent to IM compared with RTPs engaging in low-frequency post-transplant physical activity.

conclusionOur study revealed that physical activity, especially in the post-transplant stage, is closely associated with IM adherence and presents a potential intervention for improving IM adherence by RTPs.

Indexed as

Drug MonitoringExerciseImmunosuppressive AgentsKidney TransplantationAdultCase-Control StudiesChinaFemaleHumansLogistic ModelsMaleMiddle AgedTransplant RecipientsImmunosuppressive Agentsexercise testmedication adherencerenal transplantation

Identifiers

PMID39477281
PMCPMC11529692

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.