ArticleBrazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]2024
Anti-quorum sensing activity of essential oils against multidrug-resistant Klebsiella pneumoniae: a novel approach to control bacterial virulence.
Article in Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology], 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Article
- A biocompatible β-cyclodextrin inclusion complex containing natural extracts: a promising antibiofilm agent.Nanoscale advances · 2025Article
- Preparation and Properties of Chitosan Complexes Consisting ofMolecules (Basel, Switzerland) · 2025Article
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Authors and funding
2 authors.
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Abstract
The increasing resistance of microbes to conventional drugs is a serious problem worldwide that has increased the need for alternative antimicrobial compounds. Naturally occurring essential oils (EOs) are considered an important component of traditional pharmacopeia because of their antimicrobial and antioxidant properties. This has attracted researchers to identify novel therapeutic anti-pathogenic agents that could act as non-toxic quorum sensing inhibitors, thus controlling infections without encouraging the development of bacterial resistance. This prompted to undertake the current investigation to unravel the efficacy of EOs as QS modulators in reducing the virulence of multidrug resistant (MDR) strains of Klebsiella pneumoniae. The study highlighted the anti-QS activity of fifteen EOs in modulating the QS-related traits by a reduction in capsular polysaccharide, exopolysaccharide and siderophore production in addition to inhibition of biofilm formation. The overall results suggest using EOs to develop alternate intervention strategies to mitigate infections caused by MDR strains of K. pneumoniae.
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