Evidence map›Paper›PMID 39476181›Full record

ReviewArchives of microbiology2024

The clinical praxis of bacteriocins as natural anti-microbial therapeutics.

Safura Nisar, Abdul Haseeb Shah, Ruqeya Nazir

Abstract readReview
PubMed Publisher
In one paragraph

Review in Archives of microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Safura NisarDepartment of Bioresources, School of Biological Sciences, University of Kashmir, Hazratbal, Srinagar, 190006, India.
Abdul Haseeb ShahDepartment of Bioresources, School of Biological Sciences, University of Kashmir, Hazratbal, Srinagar, 190006, India. abdulhaseeb@kashmiruniversity.ac.in.ORCID http://orcid.org/0000-0003-2242-0551
Ruqeya NazirCentre of Research for Development (CORD), School of Biological Sciences, University of Kashmir, Hazratbal, Srinagar, 190006, India. ruqeya@uok.edu.in.ORCID http://orcid.org/0000-0002-1437-1895

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent decades, the excessive use of antibiotics has resulted in a rise in antimicrobial drug resistance (ADR). Annually, a significant number of human lives are lost due to resistant infectious diseases, leading to around 700,000 deaths, and it is estimated that by 2050, there could be up to 10 million casualties. Apart from their possible application as preservatives in the food sector, bacteriocins are gaining acknowledgment as potential clinical treatments. Not only this, these antimicrobial peptides have revealed in modulating the host immune system producing anti-inflammatory and anti-modulatory responses. At the same time, due to the ever-increasing global threat of antibiotic resistance, bacteriocins have gained attraction among researchers due to their potential clinical applications. Bacteriocins as antimicrobial peptides, represent one of the most important natural defense mechanisms among bacterial species, particularly lactic acid bacteria (LAB), that can fight against infection-causing pathogens. In this review, we are highlighting the potential of bacteriocins as novel therapeutics for inhibiting a wide range of clinically relevant and multi-drug-resistant pathogens (MDR). We also highlight the effectiveness and potential applications of current bacteriocin treatments in combating antimicrobial resistance (AMR), thereby promoting human health.

Indexed as

Anti-Bacterial AgentsBacteriocinsAnimalsAntimicrobial PeptidesBacteriaBacterial InfectionsDrug Resistance, Multiple, BacterialHumansLactobacillalesAnti-Bacterial AgentsAntimicrobial PeptidesBacteriocinsAntibioticsAntimicrobial resistance (AMR)BacteriocinsLactic acid bacteriaNovel therapeuticsPathogens

Identifiers

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.