Evidence map›Paper›PMID 39476179›Full record

ReviewCellular and molecular life sciences : CMLS2024

The interplay of gut microbiota, obesity, and depression: insights and interventions.

Iryna Halabitska, Pavlo Petakh, Iryna Kamyshna, Valentyn Oksenych, Denis E Kainov, Oleksandr Kamyshnyi

Abstract readReview
In one paragraph

Review in Cellular and molecular life sciences : CMLS, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Review
  4. Review
  5. Gut Microbiota and Metabolic Health: From Dysbiosis to Therapeutics.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2026
    Review
  6. Review
  7. Review
  8. Article
  9. Review
  10. Observational
  11. Review
  12. Article
  13. Recent advances in the positive role ofFrontiers in immunology · 2026
    Review
  14. War, diet, and PTSD in Ukrainian youth.Scientific reports · 2025
    Article
  15. Review
  16. Towards molecular diagnostics of parental alienation.Cellular and molecular life sciences : CMLS · 2025
    Review
  17. Review
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Iryna HalabitskaDepartment of Therapy and Family Medicine, I. Horbachevsky Ternopil National Medical University, Voli Square, 1, Ternopil, 46001, Ukraine.
Pavlo PetakhDepartment of Biochemistry and Pharmacology, Uzhhorod National University, Uzhhorod, 88000, Ukraine. pavlo.petakh@uzhnu.edu.ua.ORCID http://orcid.org/0000-0002-0860-4445
Iryna KamyshnaDepartment of Medical Rehabilitation, I. Horbachevsky Ternopil National Medical University, Ternopil, 46001, Ukraine.
Valentyn OksenychDepartment of Clinical Science, University of Bergen, Bergen, 5020, Norway.
Denis E KainovDepartment of Clinical and Molecular Medicine (IKOM), Norwegian University of Science and Technology, Trondheim, 7028, Norway. denis.kainov@ntnu.no.
Oleksandr KamyshnyiDepartment of Microbiology, Virology, and Immunology, I. Horbachevsky Ternopil National Medical University, Ternopil, 46001, Ukraine.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The gut microbiome, body weight, and related comorbidities are intricately linked through a complex interaction of microbial, genetic, environmental, and psychological factors. Alterations in gut microbiota can contribute to the development of weight disorders and depressive symptoms, with the potential for these relationships to be bidirectional. Effective management of these interconnected conditions often involves a combination of lifestyle modifications and psychological support. Medical interventions, including treatments for obesity, antidiabetic drugs, antidepressants, antibiotics, and probiotics, can have beneficial and detrimental effects on gut microbiota and mental health. Further research is needed to better understand their impact on gut microbiome and mental health in the context of obesity.

Indexed as

DepressionGastrointestinal MicrobiomeObesityAnimalsAntidepressive AgentsHumansProbioticsAntidepressive AgentsAntidepressantsDepressionGut microbiotaMental healthObesityProbiotics

Identifiers

PMID39476179
PMCPMC11525354

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.