Evidence map›Paper›PMID 39476092›Full record

ArticleNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2025

Clozapine for Parkinson's disease psychosis in a septuagenarian: a nightmare turned into bliss.

Janki Makani, Anand Kumar, Ibrahim Hussain, Niraj Kumar, Deepika Joshi

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In one paragraph

Article in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Janki MakaniDepartment of Neurology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, 221005, India.
Anand KumarDepartment of Neurology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, 221005, India.
Ibrahim HussainDepartment of Neurology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, 221005, India.
Niraj KumarDepartment of Neurology, AIIMS, Bibinagar, 508126, Telangana, India.
Deepika JoshiDepartment of Neurology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, 221005, India. drdeepikajoshi73@gmail.com.ORCID http://orcid.org/0000-0002-5224-2808

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Parkinson's disease psychosis, characterized by confusion, visual hallucinations, and delusions is a nightmare for the patients and caregivers. Classic neuroleptics aggravate the motor symptoms, hence the need for an effective atypical antipsychotic. Currently Pimavanserin is the only approved drug for Parkinson's disease psychosis (PDP), however it is not readily available. Clozapine with its excellent anti psychotic profile, without worsening of motor features, cost effectiveness and easy availability transcends all boundaries in improving the Quality of life in PD patients with psychosis. We describe an elderly patient with PDP with an excellent response to low dose clozapine.

Indexed as

Antipsychotic AgentsClozapineParkinson DiseasePsychotic DisordersAgedFemaleHumansAntipsychotic AgentsClozapineAtypical antipsychoticsClozapineParkinsons disease psychosisPimavanserin

Identifiers

PMID39476092

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.