Evidence map›Paper›PMID 39476029›Full record

ArticleMemorias do Instituto Oswaldo Cruz2024

The Oxente Chagas Bahia Project: evaluating the efficacy of a rapid diagnostic test and treatments for Chagas disease.

Fred Luciano Neves Santos, Tycha Bianca Sabaini Pavan, Cristiane Siqueira Valle, Daniel Dias Sampaio, Larissa Carvalho Medrado Vasconcelos, Maria Hermoso Cristóbal, Ângelo Antônio Oliveira Silva, Cátia Martins de Oliveira, Raquel Santos de Souza, Carmen Nila Phang Romero Casas and 2 more

Abstract read
In one paragraph

Article in Memorias do Instituto Oswaldo Cruz, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Standardization of Serodiagnostic Methods for Trypanosoma cruzi.Methods in molecular biology (Clifton, N.J.) · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Fred Luciano Neves SantosFundação Oswaldo Cruz-Fiocruz, Instituto Gonçalo Moniz, Laboratório Avançado de Saúde Pública, Salvador, BA, Brasil.ORCID http://orcid.org/0000-0002-3944-0818
Tycha Bianca Sabaini PavanFundação Oswaldo Cruz-Fiocruz, Instituto Gonçalo Moniz, Laboratório Avançado de Saúde Pública, Salvador, BA, Brasil.
Cristiane Siqueira ValleFundação Oswaldo Cruz-Fiocruz, Vice-Presidência de Pesquisa e Coleções Biológicas, Plataforma de Pesquisa Clínica, Rio de Janeiro, RJ, Brasil.
Daniel Dias SampaioFundação Oswaldo Cruz-Fiocruz, Instituto Gonçalo Moniz, Grupo de Pesquisa Interdisciplinar em Biotecnologia e Epidemiologia de Doenças Infecciosas, Salvador, BA, Brasil.
Larissa Carvalho Medrado VasconcelosFundação Oswaldo Cruz-Fiocruz, Instituto Gonçalo Moniz, Laboratório Avançado de Saúde Pública, Salvador, BA, Brasil.
Maria Hermoso CristóbalFundação Oswaldo Cruz-Fiocruz, Vice-Presidência de Pesquisa e Coleções Biológicas, Plataforma de Pesquisa Clínica, Rio de Janeiro, RJ, Brasil.
Ângelo Antônio Oliveira SilvaFundação Oswaldo Cruz-Fiocruz, Instituto Gonçalo Moniz, Laboratório Avançado de Saúde Pública, Salvador, BA, Brasil.
Cátia Martins de OliveiraFundação Oswaldo Cruz-Fiocruz, Centro de Desenvolvimento Tecnológico em Saúde, Rio de Janeiro, RJ, Brasil.
Raquel Santos de SouzaFundação Oswaldo Cruz-Fiocruz, Centro de Desenvolvimento Tecnológico em Saúde, Rio de Janeiro, RJ, Brasil.
Carmen Nila Phang Romero CasasFundação Oswaldo Cruz-Fiocruz, Centro de Desenvolvimento Tecnológico em Saúde, Rio de Janeiro, RJ, Brasil.
André DaherFundação Oswaldo Cruz-Fiocruz, Vice-Presidência de Pesquisa e Coleções Biológicas, Programa de Pesquisa Translacional em Doenças de Chagas, Rio de Janeiro, RJ, Brasil.
Isadora Cristina de SiqueiraFundação Oswaldo Cruz-Fiocruz, Instituto Gonçalo Moniz, Grupo de Pesquisa Interdisciplinar em Biotecnologia e Epidemiologia de Doenças Infecciosas, Salvador, BA, Brasil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chagas disease (CD), caused by Trypanosoma cruzi, is a life-threatening neglected anthropozoonosis primarily transmitted by triatomine bugs. Affecting an estimated 5.7 million people globally, CD has significant morbidity and mortality, particularly in Latin America. The Oxente Chagas Bahia Project aims to screen approximately 30,000 individuals, validate a rapid diagnostic test in a real-world setting, and provide crucial data on its diagnostic performance and cost-effectiveness. Additionally, a biobank will be established to support further research on disease biomarkers and treatment cure rates. By enhancing access to timely diagnosis and treatment, the project will evaluate a strategy to reduce the CD burden.

Indexed as

Chagas DiseaseTrypanosoma cruziBrazilCost-Benefit AnalysisDiagnostic Tests, RoutineHumansRapid Diagnostic TestsSensitivity and SpecificityTrypanocidal AgentsTrypanocidal Agents

Identifiers

PMID39476029
PMCPMC11520660

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.