Evidence map›Paper›PMID 39475292›Full record

ArticleInfection and immunity2024

Transiently boosting Vγ9+Vδ2+ γδ T cells early in Mtb coinfection of SIV-infected juvenile macaques does not improve Mtb host resistance.

Erica C Larson, Amy L Ellis, Mark A Rodgers, Abigail K Gubernat, Janelle L Gleim, Ryan V Moriarty, Alexis J Balgeman, Yonne T de Menezes, Cassaundra L Ameel, Daniel J Fillmore and 11 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Infection and immunity, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

21 authors.

Erica C LarsonDepartment of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.ORCID 0000-0001-5025-9369
Amy L EllisDepartment of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Mark A RodgersDepartment of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.ORCID 0000-0001-9800-3362
Abigail K GubernatDepartment of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Janelle L GleimDepartment of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Ryan V MoriartyDepartment of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, Wisconsin, USA.ORCID 0000-0001-7100-1906
Alexis J BalgemanDepartment of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Yonne T de MenezesDepartment of Immunobiology, Federal University of Santa Catarina, Florianópolis, Santa Catarina, Brazil.
Cassaundra L AmeelDepartment of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Daniel J FillmoreDepartment of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Skyler M PergalskeDepartment of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Jennifer A JunoDepartment of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, Australia.ORCID 0000-0002-9072-1017
Pauline MaielloDepartment of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Harris B ChishtiDepartment of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Philana Ling LinDepartment of Pediatrics, UPMC's Children's Hospital of the University of Pittsburgh of UPMC, Pittsburgh, Pennsylvania, USA.
Dale I GodfreyDepartment of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, Australia.
Stephen J KentDepartment of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, Australia.ORCID 0000-0002-8539-4891
Daniel G PellicciDepartment of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, Australia.
Lishomwa C NdhlovuDepartment of Medicine, Division of Infectious Disease, Weill Cornell Medicine, New York, New York, USA.ORCID 0000-0001-5427-4187
Shelby L O'ConnorDepartment of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, Wisconsin, USA.ORCID 0000-0003-0183-5010
Charles A ScangaDepartment of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.ORCID 0000-0003-3654-5603

Funding

WNPRC Supplemental Request for Nonhuman Primate Enclosures to Equip HIV/AIDS-Related Research FacilitiesP51OD011106 · OD · UNIVERSITY OF WISCONSIN-MADISON · PI Dorota A. Grejner-Brzezinska · 2012 to 2026
$150.7M
Practices CoreUC7AI180311 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI William Paul Duprex · 2023 to 2026
$13.2M
Effects of HIV SIV on unconventional T cells in immunity to M. tuberculosis in pre adolescentsR01AI142662 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI NDHLOVU, LISHOMWA C, OCONNOR, SHELBY L · 2019 to 2023
$6.2M
Re-educating T cell-mediated immunity in SIV by modulating metabolic pathwaysK01OD033539 · OD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI LARSON, ERICA CHRISTINE · 2022 to 2024
$571k
DHAC | National Health and Medical Research Council (NHMRC) 2008913,1117766NIAID NIH HHS R01 AI142662NIAID NIH HHS UC7 AI180311NIH HHS K01 OD033539NIH HHS P51 OD011106ODCDC CDC HHS K01 OD033539
6 · The paper itself

Abstract

Children living with HIV have a higher risk of developing tuberculosis (TB), a disease caused by the bacterium

Indexed as

CoinfectionMycobacterium tuberculosisReceptors, Antigen, T-Cell, gamma-deltaSimian Acquired Immunodeficiency SyndromeSimian Immunodeficiency VirusAnimalsDisease Models, AnimalImidazolesMacaca fascicularisT-LymphocytesT-Lymphocyte SubsetsTuberculosisZoledronic AcidImidazolesReceptors, Antigen, T-Cell, gamma-deltaZoledronic AcidGamma delta T cellshuman immunodeficiency virusMycobacterium tuberculosisnonhuman primatespediatric infectious diseaseT cells

Identifiers

PMID39475292
PMCPMC11629613

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.