Evidence map›Paper›PMID 39475101›Full record

ArticleCancer medicine2024

Perceptions of Multicancer Detection Tests Among Primary Care Physicians and Laypersons: A Qualitative Study.

Goli Samimi, Sarah M Temkin, Carol J Weil, Paul K J Han, Elyse LeeVan, Wendy S Rubinstein, Tessa M Swigart, Sarah Caban, Katherine Dent, Lori M Minasian

Abstract read
In one paragraph

Article in Cancer medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. A Socio-ecological Analysis of Factors Influencing the Perceived Value of Multicancer Early Detection Testing in the United States.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2026
    Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Goli SamimiDivision of Cancer Prevention, National Cancer Institute, Bethesda, Maryland, USA.ORCID https://orcid.org/0000-0002-0674-003X
Sarah M TemkinOffice of Research on Women's Health, National Institutes of Health, Bethesda, Maryland, USA.
Carol J WeilIndependent Consultant, Human Research Protections and Bioethics, Bethesda, Maryland, USA.
Paul K J HanDivision of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, Maryland, USA.
Elyse LeeVanDivision of Cancer Prevention, National Cancer Institute, Bethesda, Maryland, USA.
Wendy S RubinsteinDivision of Cancer Prevention, National Cancer Institute, Bethesda, Maryland, USA.
Tessa M SwigartICF Next, Reston, Virginia, USA.
Sarah CabanICF Next, Reston, Virginia, USA.
Katherine DentICF Next, Reston, Virginia, USA.
Lori M MinasianDivision of Cancer Prevention, National Cancer Institute, Bethesda, Maryland, USA.

Funding

Division of Cancer Prevention, National Cancer Institute 75N91021A00002
6 · The paper itself

Abstract

introductionMulticancer detection tests (MCDs) are blood-based tests designed to detect multiple cancer types. It is currently unclear whether these cancer screening tests improve mortality. To understand awareness of MCDs among providers and patients, as well as explore how they perceive the benefits, harms, and acceptability of MCDs, we have undertaken a focus group study in primary care physicians (PCPs) and laypersons to explore knowledge, attitudes, and expectations of cancer screening using MCDs.

methodsWe conducted six focus groups with 45 PCP participants and 12 focus groups with 80 layperson participants. Participants were identified via a consumer research firm and found eligible following the completion of a screener survey. Moderators used a semi-structured guide containing open-ended questions and prompts to facilitate the discussion. Recordings were transcribed and coded line by line using a codebook developed based on questions and emerging discussion concepts, and emergent themes were identified.

resultsBoth PCP and layperson participants felt the that benefits of MCDs included ease of use and potential ability to detect cancers early. However, they felt that additional data is needed to overcome some of the concerns related to MCDs. PCP participants expressed concerns related to lack of practice guidelines, cost of diagnostic follow-ups, privacy and insurance issues, fear/anxiety related to confirmation of MCD results, and malpractice liability related to perceived false negative test results. Layperson participants expressed concerns related to costs, insurance coverage, and privacy, as well as anxiety over the confirmation of a positive test result.

conclusionsThere is a major need for more rigorous data regarding MCDs to inform the development of guidelines for use as cancer screening tools.

Indexed as

Early Detection of CancerFocus GroupsHealth Knowledge, Attitudes, PracticeNeoplasmsPhysicians, Primary CareQualitative ResearchAdultAgedFemaleHumansMaleMiddle Agedcancer screeningfocus groupsMCD testsmulticancer detection testsPCPs

Identifiers

PMID39475101
PMCPMC11523003

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.