Evidence map›Paper›PMID 39475049›Full record

Trial reportInternational journal for quality in health care : journal of the International Society for Quality in Health Care2024

Effect of integrated medicines management on quality of discharge medication information-a secondary endpoint in a randomized controlled trial.

Liv Mathiesen, Tram Bich Michelle Nguyen, Ingrid Dæhlen, Morten Mowé, Marianne Lea

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in International journal for quality in health care : journal of the International Society for Quality in Health Care, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Liv MathiesenDepartment of Pharmacy, Section for Pharmacology and Pharmaceutical Biosciences, University of Oslo, Postboks 1068 Blindern, 0316 Oslo, Norway.ORCID 0000-0002-6598-2215
Tram Bich Michelle NguyenDepartment of Pharmacy, Section for Pharmacology and Pharmaceutical Biosciences, University of Oslo, Postboks 1068 Blindern, 0316 Oslo, Norway.
Ingrid DæhlenDepartment of Mathematics, University of Oslo, Postboks 1053 Blindern, 0316 Oslo, Norway.
Morten MowéDivision of Medicine, Oslo University Hospital, Postboks 4956, Nydalen, 0424 Oslo, Norway.
Marianne LeaDepartment of Pharmacy, Section for Pharmacology and Pharmaceutical Biosciences, University of Oslo, Postboks 1068 Blindern, 0316 Oslo, Norway.

Funding

South-Eastern Norway Regional Health Authority 12/00718
6 · The paper itself

Abstract

backgroundHigh-quality discharge information is important to promote patient safety when patients are transferred from hospital to primary care. Patients with multiple long-term conditions are especially vulnerable to insufficient transfer of medication information, as they use many medications and have complex interactions with the healthcare services. The aim of this study was to investigate the effect of integrated medicines management provided to hospitalized multimorbid patients on the quality of the discharge medication information.

methodsMultimorbid patients ≥18 years, using a minimum of four regular medications from a minimum of two therapeutic medication classes were recruited from the Internal Medicine ward, Oslo University Hospital, Norway, from August 2014 to March 2016 and randomly assigned, 1:1, to the intervention or control group. Intervention patients received integrated medicines management throughout the hospital stay. Control patients received standard care. This paper reports the results of a prespecified secondary endpoint analysis of the randomized controlled trial; the difference between the intervention and control group in the quality of discharge medication information.

resultsThe analysis population comprised 384 patients. Integrated medicines management improved the discharge summary quality score of the medication information from 5.8 ± 1.5 to 8.6 ± 2.6 [mean difference 2.7, 95% confidence interval (CI) 2.3-3.2, P < .001]. In total, 171 intervention patients (89%) received a patient discharge information letter, compared to 66 control patients (35%), P < .001. The quality score of the medication information in the patient discharge information letter was improved from 6.0 ± 1.8 in the control group to 10.0 ± 1.3 in the intervention group (mean difference 4.0, 95% CI 3.6-4.4, P < .001).

conclusionIntegrated medicines management delivered to multimorbid patients during a hospital stay improved the quality of the medication information in discharge summaries as well as patient discharge information letters and ensured that a discharge information letter in lay language was prepared for almost all patients who were involved in the management of their medications after discharge.

Indexed as

Patient DischargeAgedAged, 80 and overFemaleHumansMaleMedication ReconciliationMiddle AgedMultimorbidityNorwayPatient Safetycare transitiondischarge informationdischarge summaryhospital dischargeintegrated medicines managementpatient safety

Identifiers

PMID39475049
PMCPMC11630300

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.