Evidence map›Paper›PMID 39474660›Full record

ArticleJournal of cardiovascular electrophysiology2025

Left atrial functional changes associated with repeated catheter ablations for atrial fibrillation.

Jiawei Dong, Eugene Kwan, Jake A Bergquist, Derek J Dosdall, Edward V DiBella, Rob S MacLeod, Gregory J Stoddard, Klitos Konstantidinis, Benjamin A Steinberg, T Jared Bunch and 1 more

Abstract read
In one paragraph

Article in Journal of cardiovascular electrophysiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jiawei DongDepartment of Biomedical Engineering, University of Utah, Salt Lake City, Utah, USA.ORCID 0000-0003-3167-166X
Eugene KwanDepartment of Biomedical Engineering, University of Utah, Salt Lake City, Utah, USA.
Jake A BergquistDepartment of Biomedical Engineering, University of Utah, Salt Lake City, Utah, USA.
Derek J DosdallDepartment of Biomedical Engineering, University of Utah, Salt Lake City, Utah, USA.ORCID 0000-0001-5059-6824
Edward V DiBellaRadiology and Imaging Sciences, University of Utah, Salt Lake City, Utah, USA.ORCID 0000-0001-9196-3731
Rob S MacLeodDepartment of Biomedical Engineering, University of Utah, Salt Lake City, Utah, USA.ORCID 0000-0002-0000-0356
Gregory J StoddardDepartment of Internal Medicine, Division of Epidemiology, University of Utah, Salt Lake City, Utah, USA.ORCID 0000-0002-6292-276X
Klitos KonstantidinisDepartment of Internal Medicine, Division of Cardiovascular Medicine, University of Utah, Salt Lake City, Utah, USA.
Benjamin A SteinbergDepartment of Internal Medicine, Division of Cardiovascular Medicine, University of Utah, Salt Lake City, Utah, USA.ORCID 0000-0002-4729-7820
T Jared BunchDepartment of Internal Medicine, Division of Cardiovascular Medicine, University of Utah, Salt Lake City, Utah, USA.
Ravi RanjanDepartment of Biomedical Engineering, University of Utah, Salt Lake City, Utah, USA.ORCID 0000-0002-3321-2435

Funding

CTSA UM1 Program at University of UtahUM1TR004409 · NCATS · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI RACHEL HESS, Jennifer Juhl Majersik · 2023 to 2026
$21.9M
TRAINING IN CARDIOVASCULAR RESEARCHT32HL007576 · NHLBI · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI Stavros George Drakos, Robin M Shaw · 1985 to 2026
$10.6M
NCATS NIH HHS UM1 TR004409NHLBI NIH HHS T32 HL007576Nora Eccles Treadwell Foundation
6 · The paper itself

Abstract

introductionThe impact of repeated atrial fibrillation (AF) ablations on left atrial (LA) mechanical function remains uncertain, with limited long-term follow-up data.

methodsThis retrospective study involved 108 AF patients who underwent two catheter ablations with cardiac magnetic resonance imaging (MRI) done before and 3 months after each of the ablations from 2010 to 2021. The rate of change in peak longitudinal atrial strain (PLAS) assessed LA function. Additionally, a sub-study of 36 patients who underwent an extra MRI before the second ablation, gave us an additional time segment to evaluate the basis of change in PLAS.

resultsIn the two-ablation, three MRI sub-study 1, the PLAS percent change rate was similar before and after the first ablation (r

conclusionThe present study suggests that the more ablations performed, the more significant the decrease in the postablation mechanical function of the LA. The natural progression of AF (strain change from postablation 1 to pre-ablation 2) had a greater negative influence on LA mechanical function compared to the second ablation itself suggesting that second ablation in patients with recurrence after first ablation is an effective strategy even from the LA mechanical function aspect.

Indexed as

Atrial FibrillationAtrial Function, LeftCatheter AblationHeart AtriaAction PotentialsAgedFemaleHeart RateHumansMaleMiddle AgedRecurrenceReoperationRetrospective StudiesTime FactorsTreatment OutcomeAF progressionatrial fibrillationLA functionMRIrepeated ablationsstrain

Identifiers

PMID39474660
PMCPMC11726998

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.