ArticleWorld journal of hepatology2024
Prevalence and risk factors associated with metabolic dysfunction-associated steatohepatitis in patients with
Article in World journal of hepatology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Relationship betweenWorld journal of gastroenterology · 2025Article
- Therapeutic Potential of Probiotics in Metabolic Dysfunction-Associated Steatohepatitis: A Comprehensive Review.Microorganisms · 2025Review
- Association betweenWorld journal of hepatology · 2025Article
- Persistently ActiveJournal of clinical medicine · 2025Article
- Potential mechanisms and therapeutic prospects of the association betweenWorld journal of hepatology · 2025Article
- Article
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Authors and funding
11 authors.
Funding
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Abstract
background
aimTo evaluate the risk of developing MASH in patients who have had a diagnosis of
methodsThis study used a validated multicenter research database of over 360 hospitals across 26 healthcare systems across the United States from 1999 to 2022. Multivariate regression analysis assessed the risk of developing MASH, adjusting for confounders including
resultsA total of 79476132 individuals were screened in the database and 69232620 were selected in the final analysis after accounting for inclusion and exclusion criteria. Smokers (14.30%), patients with hyperlipidemia (70.35%), hypertension (73.86%), diabetes mellitus type 2 (56.46%), and obese patients (58.15%) were more common in patients with MASH compared to control. Using a multivariate regression analysis, the risk of MASH was increased in diabetics [odds ratio (OR): 3.55; 95%CI: 3.48-3.62], obese (OR: 5.93; 95%CI: 5.81-6.04), males (OR: 1.49; 95%CI: 1.46-1.52), individuals with hyperlipidemia (OR: 2.43; 95%CI: 2.38-2.49) and
conclusionThis is the largest population-based study in the United States illustrating an increased prevalence and odds of developing MASH in patients with
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