Evidence map›Paper›PMID 39474542›Full record

ArticleCase reports in oncology

JAK 2-Positive Diseases and Spontaneous Coronary Artery Dissection: Case Series.

Ahmed K A Yasin, Shehab Fareed Mohamed, Elmustafa Abdalla, Girish Rao, Abdulaziz M Alkhulaifi, Mohamed A Yassin, Deena Mudawi, Abdulrahman Fadhl Al-Mashdali, Samah Kohla, Feryal A Ibrahim and 2 more

Abstract readCase Reports
In one paragraph

Article in Case reports in oncology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Ahmed K A YasinInternal Medicine, Hamad Medical Corporation, Doha, Qatar.
Shehab Fareed MohamedHematology, Hamad Medical Corporation (HMC), Doha, Qatar.
Elmustafa AbdallaInternal Medicine, Hamad Medical Corporation, Doha, Qatar.
Girish RaoCardiothoracic Surgery, Hamad Medical Corporation, Doha, Qatar.
Abdulaziz M AlkhulaifiCardiothoracic Surgery, Hamad Medical Corporation, Doha, Qatar.
Mohamed A YassinHematology, Hamad Medical Corporation (HMC), Doha, Qatar.
Deena MudawiHematology, Hamad Medical Corporation (HMC), Doha, Qatar.
Abdulrahman Fadhl Al-MashdaliHematology, Hamad Medical Corporation (HMC), Doha, Qatar.
Samah KohlaLaboratory Medicine and Pathology, Hematology Division, Hamad Medical Corporation, Doha, Qatar.
Feryal A IbrahimLaboratory Medicine and Pathology, Haematopathology Division, Hamad Medical Corporation, Doha, Qatar.
Dina SolimanLaboratory Medicine and Pathology, Hamad Medical Corporation, Doha, Qatar.
Cornelia S CarrCardiothoracic Surgery, Hamad Medical Corporation, Doha, Qatar.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Chronic myeloproliferative neoplasms (MPNs) such as polycythaemia vera (PV) and essential thrombocytosis are associated with atherosclerosis and cardiovascular events, especially if JAK2 mutation is there. In rare cases, also spontaneous coronary artery dissection (SCAD) can be seen. Case Presentation: This case series describes two case reports of MPNs in which SCAD was found in both of them in addition to standard atherosclerosis. First one was about a 42-year-old man who was admitted for acute myocardial infarction (MI) and was later found to have PV and SCAD. The second one was about a 52-year-old man who was also admitted for acute MI and was later found to have SCAD and essential thrombocythemia. JAK2V617F missense mutation was found in both cases. Conclusion: MPNs with JAK2 mutations are associated with SCAD in addition to usual atherosclerosis. This association needs further research.

Indexed as

Coronary artery dissectionJAK2Polycythemia vera

Identifiers

PMID39474542
PMCPMC11521505

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.