Evidence map›Paper›PMID 39474529›Full record

ArticleCase reports in oncology

Chromosomal Abnormalities as a Predisposition to Secondary Neurolymphomatosis in Patients with Diffuse Large B-Cell Lymphoma: A Report of Two Cases and a Literature Review.

Naoki Watanabe, Sakiko Harada, Shoko Sato, Yasutaka Fukuda, Yuina Tanaka, Kensuke Yanashima, Eriko Sato, Daisuke Taniguchi, Yuji Tomizawa, Nobutaka Hattori and 1 more

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Case reports in oncology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Naoki WatanabeDepartment of Hematology, Juntendo University Nerima Hospital, Tokyo, Japan.
Sakiko HaradaDepartment of Hematology, Juntendo University Nerima Hospital, Tokyo, Japan.
Shoko SatoDivision of Hematology, Department of Medicine, Juntendo University School of Medicine, Tokyo, Japan.
Yasutaka FukudaDepartment of Hematology, Juntendo University Nerima Hospital, Tokyo, Japan.
Yuina TanakaDepartment of Hematology, Juntendo University Nerima Hospital, Tokyo, Japan.
Kensuke YanashimaDepartment of Hematology, Juntendo University Nerima Hospital, Tokyo, Japan.
Eriko SatoDepartment of Hematology, Juntendo University Nerima Hospital, Tokyo, Japan.
Daisuke TaniguchiDivision of Neurology, Department of Medicine, Juntendo University School of Medicine, Tokyo, Japan.
Yuji TomizawaDivision of Neurology, Department of Medicine, Juntendo University School of Medicine, Tokyo, Japan.
Nobutaka HattoriDivision of Neurology, Department of Medicine, Juntendo University School of Medicine, Tokyo, Japan.
Miki AndoDivision of Hematology, Department of Medicine, Juntendo University School of Medicine, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Neurolymphomatosis (NL) is a rare condition characterized by the infiltration of malignant lymphoma cells into the peripheral nervous system. The optimal treatment for NL remains unclear, and patients with secondary NL have a poor prognosis. Although early recognition of NL may contribute to successful treatment, the predictive factors for secondary NL are yet to be established. Case Presentation: Here, we present our investigation on the predictive factors for secondary NL, and report two cases of secondary NL with a literature review. We analyzed chromosomal abnormalities in patients with secondary NL and found a common deletion of chromosome 10 and add(11)(p11). The chromosomal abnormalities might be a predictive factor for secondary NL; therefore, confirmation of chromosomal abnormalities can possibly give a hint for early detect of secondary NL. Prompt histopathological examination or imaging techniques can lead to early diagnosis of secondary NL in patients with diffuse large B-cell lymphoma (DLBCL). Conclusion: When neurological symptoms manifest in patients with DLBCL and there are chromosomal abnormalities, the possible development of secondary NL should be considered.

Indexed as

Diffuse large B-cell lymphomaNeurolymphomatosisPredictive factor

Identifiers

PMID39474529
PMCPMC11521521

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.