Evidence map›Paper›PMID 39474126›Full record

ArticleAsian journal of pharmaceutical sciences2024

Neutrophil-targeted liposomal platform: A shift in novel approach for early detection and treatment of cancer metastasis.

Cong Li, Kexin Zhang, Zehua Cheng, Lihong Wang, Zehao Li, Chao Shen, Zhihang Li, Zeyu Wang, Lianrui Cao, Lijiang Chen

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Asian journal of pharmaceutical sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Cong LiSchool of Pharmaceutical Science, Liaoning University, Shenyang 110036, China.
Kexin ZhangSchool of Pharmaceutical Science, Liaoning University, Shenyang 110036, China.
Zehua ChengSchool of Pharmaceutical Science, Liaoning University, Shenyang 110036, China.
Lihong WangSchool of Pharmaceutical Science, Liaoning University, Shenyang 110036, China.
Zehao LiSchool of Pharmaceutical Science, Liaoning University, Shenyang 110036, China.
Chao ShenSchool of Pharmaceutical Science, Liaoning University, Shenyang 110036, China.
Zhihang LiSchool of Pharmaceutical Science, Liaoning University, Shenyang 110036, China.
Zeyu WangSchool of Pharmaceutical Science, Liaoning University, Shenyang 110036, China.
Lianrui CaoSchool of Pharmaceutical Science, Liaoning University, Shenyang 110036, China.
Lijiang ChenSchool of Pharmaceutical Science, Liaoning University, Shenyang 110036, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tumor metastasis is responsible for 90 % of cancer-associated deaths, and its early detection may decrease the likelihood of mortality. Studies have demonstrated that metastasis results from the interaction between "seeds" (tumor cells) and "soil" (pre-metastatic niche, PMN). As the first and most abundant immune cells to be recruited to PMN, neutrophils play a key role in the ultimate formation of metastatic foci through mechanisms such as supporting tumor cell growth, promoting angiogenesis, and shaping an immune-suppressive microenvironment. In this study, two distinct types of sialic acid (SA)-modified liposomes were prepared to target and regulate pro-metastatic neutrophils through the

Indexed as

Early depletionLiposomeLung metastasisNeutrophilPre-metastatic nicheSialic acid

Identifiers

PMID39474126
PMCPMC11513460

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.