Evidence map›Paper›PMID 39474123›Full record

ArticleInternational journal of nanomedicine2024

Mesoporous Polydopamine Nanotherapeutics for MRI-Guided Cancer Photothermal and Anti-Inflammatory Therapy.

Yang Liu, Chunan Wang, Sitong Liu, Hangzhan- Ma, Jiayun Xu, Kai Jiang, Ruitao Lu, Xintao Shuai, Jinming Wang, Zhong Cao

Abstract read
In one paragraph

Article in International journal of nanomedicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Biomedical Applications of Gadolinium-Containing Biomaterials: Not Only MRI Contrast Agent.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yang Liu *School of Biomedical Engineering, Sun Yat-Sen University, Guangzhou, Guangdong, People's Republic of China.
Chunan Wang *School of Biomedical Engineering, Sun Yat-Sen University, Guangzhou, Guangdong, People's Republic of China.
Sitong Liu *School of Biomedical Engineering, Sun Yat-Sen University, Guangzhou, Guangdong, People's Republic of China.
Hangzhan- MaDepartment of Orthopedics, Panyu Hospital of Chinese Medicine, Guangzhou, Guangdong, People's Republic of China.
Jiayun XuDepartment of Oral Implantology, Guanghua School of Stomatology, Hospital of Stomatology, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Stomatology, Guangzhou, People's Republic of China.
Kai JiangSchool of Biomedical Engineering, Sun Yat-Sen University, Guangzhou, Guangdong, People's Republic of China.
Ruitao LuShenzhen International Institute for Biomedical Research, Shenzhen, Guangdong, People's Republic of China.
Xintao ShuaiNanomedicine Research Center, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, Guangdong, People's Republic of China.ORCID 0000-0003-4271-0310
Jinming WangDepartment of Oral Implantology, Guanghua School of Stomatology, Hospital of Stomatology, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Stomatology, Guangzhou, People's Republic of China.
Zhong CaoSchool of Biomedical Engineering, Sun Yat-Sen University, Guangzhou, Guangdong, People's Republic of China.ORCID 0000-0003-4004-1037

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: As a burgeoning cancer treatment modality, photothermal therapy (PTT) has shown robust anti-tumor effects. However, it still faces numerous challenges, such as triggering an inflammatory response and potentially increasing the risk of cancer recurrence. To address these concerns, integration of PTT with anti-inflammatory therapies presents a promising approach to enhance the efficacy of cancer treatment and meanwhile reduce the risk of recurrence. Methods: In this study, Gd Results: The incorporation of Arg doping into MAGM NPs was intended to boost its photothermal conversion efficiency and reactive oxygen species (ROS) scavenging ability. Additionally, synergizing with the anti-inflammatory agent meloxicam (MX) within the nanoparticles aimed to enhance the anti-inflammatory effect following photothermal therapy. Furthermore, gadolinium ions (Gd

Indexed as

Anti-Inflammatory AgentsIndolesMagnetic Resonance ImagingNanoparticlesPolymersAnimalsArginineBreast NeoplasmsCell Line, TumorFemaleGadoliniumHumansMeloxicamMiceMice, Inbred BALB CPhotothermal TherapyAnti-Inflammatory AgentsArginineGadoliniumIndolesMeloxicampolydopaminePolymersReactive Oxygen Speciesanti-inflammatory therapycancer therapymagnetic resonance imagingmesoporous polydopaminephotothermal therapy

Identifiers

PMID39474123
PMCPMC11520923

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.