Evidence map›Paper›PMID 39474002›Full record

ArticleEplasty2024

Effect of Tissue Expanders Filled With Saline Versus Air on Longitudinal Breast Reconstruction Outcomes.

Mohammed Shaheen, Rachna Goli, Pooja Yesantharao, Connor Arquette, Nathan Makarewicz, Rahim S Nazerali

Abstract read
In one paragraph

Article in Eplasty, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mohammed ShaheenDivision of Plastic and Reconstructive Surgery, Stanford University School of Medicine, Stanford, California.
Rachna GoliDivision of Plastic Surgery, Warren Alpert Medical School of Brown University, Providence, Rhode Island.
Pooja YesantharaoDivision of Plastic and Reconstructive Surgery, Stanford University School of Medicine, Stanford, California.
Connor ArquetteDivision of Plastic and Reconstructive Surgery, Stanford University School of Medicine, Stanford, California.
Nathan MakarewiczDivision of Plastic and Reconstructive Surgery, Stanford University School of Medicine, Stanford, California.
Rahim S NazeraliDivision of Plastic and Reconstructive Surgery, Stanford University School of Medicine, Stanford, California.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Intraoperative expansion with air, as compared with saline, has been associated with fewer first-stage complications in 2-stage expander-implant breast reconstruction. However, longitudinal reconstructive outcomes, postoperative medication use indicating pain or discomfort, as well as patient-reported outcome measures after intraoperative air versus saline fill have not yet been investigated. Methods: This is a retrospective cohort investigation of 69 patients who underwent 2-stage expander-implant prepectoral breast reconstruction with acellular dermal matrix in 2017 and 2018. Patients underwent intraoperative tissue expander (TE) fill with air or saline during stage 1 of reconstruction and underwent expander-implant exchange in stage 2. Air versus saline cohorts were compared with regards to time to definitive reconstruction and postoperative pain/opioid use. Results: Of the 69 patients studied, 47 (68.1%) had tissue expanders filled with air and 22 (31.9%) filled with saline. In multivariable regression analysis, air-filled TEs were associated with significantly lower odds of requiring an opioid prescription refill (adjusted odds ratio [aOR] = 0.27; Conclusions: Intraoperative air versus saline TE fill appears to impact longitudinal reconstructive outcomes in expander-implant based reconstruction. Our results demonstrated that air-filled TEs were associated with significantly lower odds of opioid refills and breast pain. Our study also indicates that timing and office visits between stages do not appear to be affected by TE fill medium.

Indexed as

Air Expansionbreast implantsbreast reconstructiontissue expanderstissue expansion

Identifiers

PMID39474002
PMCPMC11520362

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.