ArticleAlzheimer's & dementia (Amsterdam, Netherlands)
Marital dissolution and cognition: The mediating effect of Aβ neuropathology.
Article in Alzheimer's & dementia (Amsterdam, Netherlands). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed.
- Gender, Marital Histories, and Cognitive Impairment in Later Life: Does Remarriage Disadvantage Women?Innovation in aging · 2025Article
- Marital dissolution and cognition: The mediating effect of Aβ neuropathology.Alzheimer's & dementia (Amsterdam, Netherlands)Article
- The Association Between Divorce and Late-life Brain Health in a Racially and Ethnically Diverse Cohort of Older Adults.Alzheimer disease and associated disordersObservational
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Authors and funding
7 authors.
Funding
Abstract
introductionWidowhood and divorce are extremely stressful life events that are associated with dementia, but the neurobiological underpinnings of this risk remain unknown. Amyloid beta (Aβ) load may explain influences of chronic stress, commonly seen in disruptive marital transitions, on cognitive decline.
methodsWe examined whether Aβ quantified by tracer uptake on positron emission tomography mediates associations between marital dissolution and executive functioning and episodic memory performance using data from 543 cognitively normal (CN) participants from the Alzheimer's Disease Neuroimaging Initiative.
resultsMarriage dissolution was associated with increased Aβ burden ( DISCUSSION: Findings suggest that stressful life events, such as the dissolution of one's marriage, might exert an effect on Alzheimer's disease proteinopathy, which may subsequently influence poor cognition.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.