ArticleNeurology. Clinical practice2025
Clinical Implementation of fMRI and EEG to Detect Cognitive Motor Dissociation: Lessons Learned in an Acute Care Hospital.
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Article in Neurology. Clinical practice, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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13citing papers in PubMed
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Who cites it
13 citing papers in PubMed.
- Neuroprognostication After Cardiac Arrest: From Test-Centered Prediction to Ethically Constrained, Longitudinal Decision-Making.Neurocritical care · 2026Article
- From fMRI to Family Meeting: Clinician and Family Perspectives on Neurotechnology-Informed Shared Decision-Making in Disorders of Consciousness.Neurocritical care · 2026Article
- Covert Consciousness: Epistemic Limits of Its Definition and Detection.Neurocritical care · 2026Review
- Disorders of consciousness diagnosis, interventions, and prognostication for the intensivist: Report of the 2025 ISICEM roundtable.Intensive care medicine · 2026Review
- Functional fractionation of large-scale brain networks in the human subcortex.bioRxiv : the preprint server for biology · 2025Article
- Surface EEG to identify cognitive motor dissociation after acute brain injury PREPRINT.medRxiv : the preprint server for health sciences · 2025Article
- Early Detection of Covert Consciousness With Functional Near-Infrared Spectroscopy.Annals of neurology · 2025Article
- Emerging issues in the management of patients with disorders of consciousness.Journal of neurology · 2025Review
- Functional neuroimaging in disorders of consciousness: towards clinical implementation.Brain : a journal of neurology · 2025Review
- Ethically Translating Advanced Neurotechnologies for Disorders of Consciousness: A Survey of Clinicians' Perspectives.Neurocritical care · 2025Article
- Using artificial intelligence to optimize anti-seizure treatment and EEG-guided decisions in severe brain injury.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025Review
- Disclosing Results of Tests for Covert Consciousness: A Framework for Ethical Translation.Neurocritical care · 2024Review
- Covert consciousness.NeuroRehabilitation · 2024Article
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Authors and funding
17 authors.
Yelena G BodienCenter for Neurotechnology and Neurorecovery (YGB, MF, HJF, WRS, AM, PKL, DF, LRH, SSC, MJY, BLE), Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA; Department of Physical Medicine and Rehabilitation (YGB), Spaulding Rehabilitation Hospital and Harvard Medical School, Charlestown, MA; Geisel School of Medicine at Dartmouth Medical School College (WRS), Hanover, NH; Athinoula A. Martinos Center for Biomedical Imaging (JEK, BLE), Massachusetts General Hospital, Charlestown, MA; Department of Radiology (JEK, JHH, PWS, OR), Massachusetts General Hospital and Harvard Medical School, Boston, MA; Department of Neurology (DF), Hospital of the University of Pennsylvania, Philadelphia, PA; and Departments of Neurology (JC) and Medicine (ER), Massachusetts General Hospital and Harvard Medical School, Boston, MA.ORCID https://orcid.org/0000-0003-4858-2903
Matteo FecchioCenter for Neurotechnology and Neurorecovery (YGB, MF, HJF, WRS, AM, PKL, DF, LRH, SSC, MJY, BLE), Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA; Department of Physical Medicine and Rehabilitation (YGB), Spaulding Rehabilitation Hospital and Harvard Medical School, Charlestown, MA; Geisel School of Medicine at Dartmouth Medical School College (WRS), Hanover, NH; Athinoula A. Martinos Center for Biomedical Imaging (JEK, BLE), Massachusetts General Hospital, Charlestown, MA; Department of Radiology (JEK, JHH, PWS, OR), Massachusetts General Hospital and Harvard Medical School, Boston, MA; Department of Neurology (DF), Hospital of the University of Pennsylvania, Philadelphia, PA; and Departments of Neurology (JC) and Medicine (ER), Massachusetts General Hospital and Harvard Medical School, Boston, MA.ORCID https://orcid.org/0000-0002-0347-8531
Holly J FreemanCenter for Neurotechnology and Neurorecovery (YGB, MF, HJF, WRS, AM, PKL, DF, LRH, SSC, MJY, BLE), Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA; Department of Physical Medicine and Rehabilitation (YGB), Spaulding Rehabilitation Hospital and Harvard Medical School, Charlestown, MA; Geisel School of Medicine at Dartmouth Medical School College (WRS), Hanover, NH; Athinoula A. Martinos Center for Biomedical Imaging (JEK, BLE), Massachusetts General Hospital, Charlestown, MA; Department of Radiology (JEK, JHH, PWS, OR), Massachusetts General Hospital and Harvard Medical School, Boston, MA; Department of Neurology (DF), Hospital of the University of Pennsylvania, Philadelphia, PA; and Departments of Neurology (JC) and Medicine (ER), Massachusetts General Hospital and Harvard Medical School, Boston, MA.ORCID https://orcid.org/0009-0004-8217-2937
William R SandersCenter for Neurotechnology and Neurorecovery (YGB, MF, HJF, WRS, AM, PKL, DF, LRH, SSC, MJY, BLE), Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA; Department of Physical Medicine and Rehabilitation (YGB), Spaulding Rehabilitation Hospital and Harvard Medical School, Charlestown, MA; Geisel School of Medicine at Dartmouth Medical School College (WRS), Hanover, NH; Athinoula A. Martinos Center for Biomedical Imaging (JEK, BLE), Massachusetts General Hospital, Charlestown, MA; Department of Radiology (JEK, JHH, PWS, OR), Massachusetts General Hospital and Harvard Medical School, Boston, MA; Department of Neurology (DF), Hospital of the University of Pennsylvania, Philadelphia, PA; and Departments of Neurology (JC) and Medicine (ER), Massachusetts General Hospital and Harvard Medical School, Boston, MA.ORCID https://orcid.org/0000-0003-4536-9357
Anogue MeydanCenter for Neurotechnology and Neurorecovery (YGB, MF, HJF, WRS, AM, PKL, DF, LRH, SSC, MJY, BLE), Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA; Department of Physical Medicine and Rehabilitation (YGB), Spaulding Rehabilitation Hospital and Harvard Medical School, Charlestown, MA; Geisel School of Medicine at Dartmouth Medical School College (WRS), Hanover, NH; Athinoula A. Martinos Center for Biomedical Imaging (JEK, BLE), Massachusetts General Hospital, Charlestown, MA; Department of Radiology (JEK, JHH, PWS, OR), Massachusetts General Hospital and Harvard Medical School, Boston, MA; Department of Neurology (DF), Hospital of the University of Pennsylvania, Philadelphia, PA; and Departments of Neurology (JC) and Medicine (ER), Massachusetts General Hospital and Harvard Medical School, Boston, MA.ORCID https://orcid.org/0009-0003-9520-5198
Phoebe K LawrenceCenter for Neurotechnology and Neurorecovery (YGB, MF, HJF, WRS, AM, PKL, DF, LRH, SSC, MJY, BLE), Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA; Department of Physical Medicine and Rehabilitation (YGB), Spaulding Rehabilitation Hospital and Harvard Medical School, Charlestown, MA; Geisel School of Medicine at Dartmouth Medical School College (WRS), Hanover, NH; Athinoula A. Martinos Center for Biomedical Imaging (JEK, BLE), Massachusetts General Hospital, Charlestown, MA; Department of Radiology (JEK, JHH, PWS, OR), Massachusetts General Hospital and Harvard Medical School, Boston, MA; Department of Neurology (DF), Hospital of the University of Pennsylvania, Philadelphia, PA; and Departments of Neurology (JC) and Medicine (ER), Massachusetts General Hospital and Harvard Medical School, Boston, MA.ORCID https://orcid.org/0009-0008-5121-4312
John E KirschCenter for Neurotechnology and Neurorecovery (YGB, MF, HJF, WRS, AM, PKL, DF, LRH, SSC, MJY, BLE), Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA; Department of Physical Medicine and Rehabilitation (YGB), Spaulding Rehabilitation Hospital and Harvard Medical School, Charlestown, MA; Geisel School of Medicine at Dartmouth Medical School College (WRS), Hanover, NH; Athinoula A. Martinos Center for Biomedical Imaging (JEK, BLE), Massachusetts General Hospital, Charlestown, MA; Department of Radiology (JEK, JHH, PWS, OR), Massachusetts General Hospital and Harvard Medical School, Boston, MA; Department of Neurology (DF), Hospital of the University of Pennsylvania, Philadelphia, PA; and Departments of Neurology (JC) and Medicine (ER), Massachusetts General Hospital and Harvard Medical School, Boston, MA.ORCID https://orcid.org/0000-0002-0389-9475
David FischerCenter for Neurotechnology and Neurorecovery (YGB, MF, HJF, WRS, AM, PKL, DF, LRH, SSC, MJY, BLE), Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA; Department of Physical Medicine and Rehabilitation (YGB), Spaulding Rehabilitation Hospital and Harvard Medical School, Charlestown, MA; Geisel School of Medicine at Dartmouth Medical School College (WRS), Hanover, NH; Athinoula A. Martinos Center for Biomedical Imaging (JEK, BLE), Massachusetts General Hospital, Charlestown, MA; Department of Radiology (JEK, JHH, PWS, OR), Massachusetts General Hospital and Harvard Medical School, Boston, MA; Department of Neurology (DF), Hospital of the University of Pennsylvania, Philadelphia, PA; and Departments of Neurology (JC) and Medicine (ER), Massachusetts General Hospital and Harvard Medical School, Boston, MA.ORCID https://orcid.org/0000-0001-8181-0643
Joseph CohenCenter for Neurotechnology and Neurorecovery (YGB, MF, HJF, WRS, AM, PKL, DF, LRH, SSC, MJY, BLE), Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA; Department of Physical Medicine and Rehabilitation (YGB), Spaulding Rehabilitation Hospital and Harvard Medical School, Charlestown, MA; Geisel School of Medicine at Dartmouth Medical School College (WRS), Hanover, NH; Athinoula A. Martinos Center for Biomedical Imaging (JEK, BLE), Massachusetts General Hospital, Charlestown, MA; Department of Radiology (JEK, JHH, PWS, OR), Massachusetts General Hospital and Harvard Medical School, Boston, MA; Department of Neurology (DF), Hospital of the University of Pennsylvania, Philadelphia, PA; and Departments of Neurology (JC) and Medicine (ER), Massachusetts General Hospital and Harvard Medical School, Boston, MA.ORCID https://orcid.org/0009-0003-8725-984X
Emily RubinCenter for Neurotechnology and Neurorecovery (YGB, MF, HJF, WRS, AM, PKL, DF, LRH, SSC, MJY, BLE), Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA; Department of Physical Medicine and Rehabilitation (YGB), Spaulding Rehabilitation Hospital and Harvard Medical School, Charlestown, MA; Geisel School of Medicine at Dartmouth Medical School College (WRS), Hanover, NH; Athinoula A. Martinos Center for Biomedical Imaging (JEK, BLE), Massachusetts General Hospital, Charlestown, MA; Department of Radiology (JEK, JHH, PWS, OR), Massachusetts General Hospital and Harvard Medical School, Boston, MA; Department of Neurology (DF), Hospital of the University of Pennsylvania, Philadelphia, PA; and Departments of Neurology (JC) and Medicine (ER), Massachusetts General Hospital and Harvard Medical School, Boston, MA.ORCID https://orcid.org/0000-0002-1788-3618
Julian H HeCenter for Neurotechnology and Neurorecovery (YGB, MF, HJF, WRS, AM, PKL, DF, LRH, SSC, MJY, BLE), Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA; Department of Physical Medicine and Rehabilitation (YGB), Spaulding Rehabilitation Hospital and Harvard Medical School, Charlestown, MA; Geisel School of Medicine at Dartmouth Medical School College (WRS), Hanover, NH; Athinoula A. Martinos Center for Biomedical Imaging (JEK, BLE), Massachusetts General Hospital, Charlestown, MA; Department of Radiology (JEK, JHH, PWS, OR), Massachusetts General Hospital and Harvard Medical School, Boston, MA; Department of Neurology (DF), Hospital of the University of Pennsylvania, Philadelphia, PA; and Departments of Neurology (JC) and Medicine (ER), Massachusetts General Hospital and Harvard Medical School, Boston, MA.ORCID https://orcid.org/0000-0002-4779-1538
Pamela W SchaeferCenter for Neurotechnology and Neurorecovery (YGB, MF, HJF, WRS, AM, PKL, DF, LRH, SSC, MJY, BLE), Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA; Department of Physical Medicine and Rehabilitation (YGB), Spaulding Rehabilitation Hospital and Harvard Medical School, Charlestown, MA; Geisel School of Medicine at Dartmouth Medical School College (WRS), Hanover, NH; Athinoula A. Martinos Center for Biomedical Imaging (JEK, BLE), Massachusetts General Hospital, Charlestown, MA; Department of Radiology (JEK, JHH, PWS, OR), Massachusetts General Hospital and Harvard Medical School, Boston, MA; Department of Neurology (DF), Hospital of the University of Pennsylvania, Philadelphia, PA; and Departments of Neurology (JC) and Medicine (ER), Massachusetts General Hospital and Harvard Medical School, Boston, MA.ORCID https://orcid.org/0000-0002-4222-6134
Leigh R HochbergCenter for Neurotechnology and Neurorecovery (YGB, MF, HJF, WRS, AM, PKL, DF, LRH, SSC, MJY, BLE), Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA; Department of Physical Medicine and Rehabilitation (YGB), Spaulding Rehabilitation Hospital and Harvard Medical School, Charlestown, MA; Geisel School of Medicine at Dartmouth Medical School College (WRS), Hanover, NH; Athinoula A. Martinos Center for Biomedical Imaging (JEK, BLE), Massachusetts General Hospital, Charlestown, MA; Department of Radiology (JEK, JHH, PWS, OR), Massachusetts General Hospital and Harvard Medical School, Boston, MA; Department of Neurology (DF), Hospital of the University of Pennsylvania, Philadelphia, PA; and Departments of Neurology (JC) and Medicine (ER), Massachusetts General Hospital and Harvard Medical School, Boston, MA.ORCID https://orcid.org/0000-0003-0261-2273
Otto RapalinoCenter for Neurotechnology and Neurorecovery (YGB, MF, HJF, WRS, AM, PKL, DF, LRH, SSC, MJY, BLE), Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA; Department of Physical Medicine and Rehabilitation (YGB), Spaulding Rehabilitation Hospital and Harvard Medical School, Charlestown, MA; Geisel School of Medicine at Dartmouth Medical School College (WRS), Hanover, NH; Athinoula A. Martinos Center for Biomedical Imaging (JEK, BLE), Massachusetts General Hospital, Charlestown, MA; Department of Radiology (JEK, JHH, PWS, OR), Massachusetts General Hospital and Harvard Medical School, Boston, MA; Department of Neurology (DF), Hospital of the University of Pennsylvania, Philadelphia, PA; and Departments of Neurology (JC) and Medicine (ER), Massachusetts General Hospital and Harvard Medical School, Boston, MA.ORCID https://orcid.org/0000-0002-5038-4183
Sydney S CashCenter for Neurotechnology and Neurorecovery (YGB, MF, HJF, WRS, AM, PKL, DF, LRH, SSC, MJY, BLE), Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA; Department of Physical Medicine and Rehabilitation (YGB), Spaulding Rehabilitation Hospital and Harvard Medical School, Charlestown, MA; Geisel School of Medicine at Dartmouth Medical School College (WRS), Hanover, NH; Athinoula A. Martinos Center for Biomedical Imaging (JEK, BLE), Massachusetts General Hospital, Charlestown, MA; Department of Radiology (JEK, JHH, PWS, OR), Massachusetts General Hospital and Harvard Medical School, Boston, MA; Department of Neurology (DF), Hospital of the University of Pennsylvania, Philadelphia, PA; and Departments of Neurology (JC) and Medicine (ER), Massachusetts General Hospital and Harvard Medical School, Boston, MA.ORCID https://orcid.org/0000-0002-4557-6391
Michael J YoungCenter for Neurotechnology and Neurorecovery (YGB, MF, HJF, WRS, AM, PKL, DF, LRH, SSC, MJY, BLE), Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA; Department of Physical Medicine and Rehabilitation (YGB), Spaulding Rehabilitation Hospital and Harvard Medical School, Charlestown, MA; Geisel School of Medicine at Dartmouth Medical School College (WRS), Hanover, NH; Athinoula A. Martinos Center for Biomedical Imaging (JEK, BLE), Massachusetts General Hospital, Charlestown, MA; Department of Radiology (JEK, JHH, PWS, OR), Massachusetts General Hospital and Harvard Medical School, Boston, MA; Department of Neurology (DF), Hospital of the University of Pennsylvania, Philadelphia, PA; and Departments of Neurology (JC) and Medicine (ER), Massachusetts General Hospital and Harvard Medical School, Boston, MA.ORCID https://orcid.org/0000-0001-6661-0811
Brian L EdlowCenter for Neurotechnology and Neurorecovery (YGB, MF, HJF, WRS, AM, PKL, DF, LRH, SSC, MJY, BLE), Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA; Department of Physical Medicine and Rehabilitation (YGB), Spaulding Rehabilitation Hospital and Harvard Medical School, Charlestown, MA; Geisel School of Medicine at Dartmouth Medical School College (WRS), Hanover, NH; Athinoula A. Martinos Center for Biomedical Imaging (JEK, BLE), Massachusetts General Hospital, Charlestown, MA; Department of Radiology (JEK, JHH, PWS, OR), Massachusetts General Hospital and Harvard Medical School, Boston, MA; Department of Neurology (DF), Hospital of the University of Pennsylvania, Philadelphia, PA; and Departments of Neurology (JC) and Medicine (ER), Massachusetts General Hospital and Harvard Medical School, Boston, MA.ORCID https://orcid.org/0000-0001-7235-8456
Funding
A functional brain network to detect and predict consciousness recoveryK23NS136745 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI David Jacobson Fischer · 2025 to 2026
$440kNINDS NIH HHS K23 NS136745
Abstract
Background: Cognitive motor dissociation (CMD) occurs when patients with severe brain injury follow commands on task-based functional MRI or EEG assessment despite demonstrating no behavioral evidence of language function. Recognizing the value of identifying patients with CMD, evidence-based guidelines published in the United States and Europe now recommend that these assessments are conducted as part of clinical care for select patients. Recent Findings: We describe our institutionally supported approach for clinical assessment of CMD and report lessons learned so that other centers can more easily implement these evaluations. Among the key lessons are the need to consider ethical implications of CMD assessment; establish standardized local protocols for patient selection, data acquisition, analysis, and interpretation; and develop effective strategies for communication of test results. Implications for Practice: Independent validation of methods to assess CMD is not available. Our approach for clinical CMD assessment is intended to be flexible, allowing for iterative improvements as the evidence base grows.
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