Evidence map›Paper›PMID 39473907›Full record

ArticleMedComm2024

N6-methyladenosine reader YTHDF3-mediated zinc finger protein 41 inhibits hepatocellular carcinoma progression by transcriptional repression of Snail.

Xinxin Li, Mengzhen Han, He Zhu, Hongwei Zhang, Yonglong Pan, Huifang Liang, Zhibin Liao, Bixiang Zhang, Xiaoping Chen

Abstract read
In one paragraph

Article in MedComm, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. The mMolecular biomedicine · 2025
    Review
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xinxin LiHepatic Surgery Center Tongji Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan Hubei China.ORCID https://orcid.org/0009-0004-2326-8760
Mengzhen HanHepatic Surgery Center Tongji Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan Hubei China.
He ZhuHepatic Surgery Center Tongji Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan Hubei China.
Hongwei ZhangHepatic Surgery Center Tongji Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan Hubei China.
Yonglong PanHepatic Surgery Center Tongji Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan Hubei China.
Huifang LiangHepatic Surgery Center Tongji Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan Hubei China.ORCID https://orcid.org/0000-0001-6874-3634
Zhibin LiaoHepatic Surgery Center Tongji Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan Hubei China.
Bixiang ZhangHepatic Surgery Center Tongji Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan Hubei China.
Xiaoping ChenHepatic Surgery Center Tongji Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan Hubei China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Advanced metastasis of hepatocellular carcinoma (HCC) significantly contributes to high death rates among patients. The efficiency of targeted therapies and chemotherapeutic agents shows individual variability. Therefore, there is no effective treatment for advanced HCC. Zinc finger proteins (ZFPs) are known to be crucial in various tumors, especially on HCC. In our study, we verified that ZFP41 could suppress the progression and metastasis of HCC through in vitro and in vivo experiments. During the past years, N6-methyladenine (m

Indexed as

EMThepatocellular carcinomam6Atranscription regulationZFP41

Identifiers

PMID39473907
PMCPMC11518695

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.