ReviewEnvironment & health (Washington, D.C.)2023
Influence of Exposure Pathways on Tissue Distribution and Health Impact of Polycyclic Aromatic Hydrocarbon Derivatives.
Review in Environment & health (Washington, D.C.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed.
- Particulate Matter-Induced Skin Injury: A Dual-Pathway AhR-Nrf2 Framework for Epidermal Homeostasis and Therapeutic Targeting.International journal of molecular sciences · 2026Review
- Article
- Pregnancy Exposure to Polycyclic Aromatic Hydrocarbons (PAHs): Exploratory Comparative Levels in Blood Serum Samples from Different Regions in Antioquia, Colombia.Journal of xenobiotics · 2026Article
- Nontarget Screening and Health Risk of Hazardous Volatile and Semivolatile Organic Compounds in Premade Food Using a Molecular Network Assisted Data Collation Workflow.Environment & health (Washington, D.C.) · 2026Article
- Heat-Induced Toxicants: Sensory Appeal Distracts Consumers' Attention From Potential Toxicological Risks of Thermally Processed Foods.Food science & nutrition · 2026Review
- Polycyclic aromatic hydrocarbon derivative 3-hydroxybenz[a]anthracene promotes the progression of T47D breast cancer cells by modulating relevant protein expression.Frontiers in cell and developmental biology · 2026Article
- Investigating the neuroprotective potentials ofCurrent research in physiology · 2026Article
- SERS and SEIRA Detection of Polycyclic Aromatic Hydrocarbons and their Derivatives in Murine Tissues: Bioaccumulation and Clearance.Journal of Raman spectroscopy : JRS · 2025Article
- Determination of Selected Hydroxylated PAHs in Urine Samples of Individuals Consuming Grilled Marshmallows.Molecules (Basel, Switzerland) · 2025Article
- Integrative analysis of lung adenocarcinoma across diverse ethnicities and exposures.Cancer cell · 2025Article
- Prevalence of Polyhalogenated Carbazole in an Anthropogenically Impacted Soil Groundwater System.Environment & health (Washington, D.C.) · 2025Article
- Exposure-Response Associations of Ambient Heavy Metal and Persistent Organic Pollutant with All-Cause and Cause-Specific Mortality: A Prospective Cohort Study.Environment & health (Washington, D.C.) · 2025Article
- Machine learning-enhanced surface-enhanced spectroscopic detection of polycyclic aromatic hydrocarbons in the human placenta.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Assessing the Impact of Pre-Soaking to Enhance Laundering Efficacy of Firefighter Turnout Gear.Toxics · 2024Article
- Exposure to Environmental Toxins: Potential Implications for Stroke Risk via the Gut- and Lung-Brain Axis.Cells · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The oxygen (OPAHs), nitro (NPAHs), hydroxyl (OH-PAHs), and alkylated (APAHs) derivatives of polycyclic aromatic hydrocarbon (PAHs) are ubiquitous pollutants in the environment. The concentrations of NPAHs, OPAHs, OH-PAHs, and APAHs are lower than that of PAHs in the environment, but the carcinogenic abilities of the derivatives are usually 10 to 1,000-fold higher than that of parent PAHs. There are three main pathways for the exposure of polycyclic aromatic compounds to humans, including inhalation, direct contact, and ingestion. After exposure by inhalation, they are mainly distributed in the lungs, affecting lung function and causing inflammation, asthma, etc. Due to the digestive system's strong capacity for metabolism, intake of PAHs and the derivatives is primarily distributed in the digestive system and metabolized there. And it may lead to dysplasia of these organs and even to cancer. The skin is the primary site of direct contact with PAH derivatives. PAH derivatives can enter the bloodstream through all three contact pathways, thereby accumulating in various organs. This study aimed to summarize the influence of exposure pathways on tissue distribution and the health impact of PAH derivatives to provide references for future research and evaluation on public health.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.