Evidence map›Paper›PMID 39473507›Full record

ReviewFrontiers in endocrinology2024

Systemic treatments for radioiodine-refractory thyroid cancers.

Piaohong Chen, Yu Yao, Huiwen Tan, Jianwei Li

Abstract readReview
In one paragraph

Review in Frontiers in endocrinology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Review
  9. CD66bMedicina (Kaunas, Lithuania) · 2025
    Article
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  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Piaohong Chen *Division of Endocrinology and Metabolism, West China Hospital of Sichuan University, Chengdu, China.
Yu Yao *Division of Endocrinology and Metabolism, West China Hospital of Sichuan University, Chengdu, China.
Huiwen TanDivision of Endocrinology and Metabolism, West China Hospital of Sichuan University, Chengdu, China.
Jianwei LiDivision of Endocrinology and Metabolism, West China Hospital of Sichuan University, Chengdu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Differentiated thyroid cancers (DTCs) constitute the primary histological subtype within thyroid cancer. Due to DTCs' distinctive radioiodine (RAI) uptake mechanism, standard treatment involving surgery, with or without adjunctive therapy using RAI and levothyroxine inhibition, typically yields favorable prognoses for the majority of patients with DTCs. However, this favorable outcome does not extend to individuals with decreased RAI uptake, termed radioiodine-refractory thyroid cancers (RAI-RTCs). Recent research has revealed that the genetic mutations and gene rearrangements affecting sites such as

Indexed as

Iodine RadioisotopesThyroid NeoplasmsAntineoplastic AgentsHumansProtein Kinase InhibitorsRadiation ToleranceAntineoplastic AgentsIodine RadioisotopesProtein Kinase Inhibitorsmitogen-activated protein kinasephosphatidylinositol-3-hydroxykinaseradioiodine-refractory thyroid cancerssodium/iodide symportersystemic treatmentsTERTptyrosine kinase inhibitors

Identifiers

PMID39473507
PMCPMC11518755

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.