Evidence map›Paper›PMID 39473459›Full record

ArticleChemical & biomedical imaging2024

Enhanced β-Amyloid Aggregation in Living Cells Imaged with Quinolinium-Based Spontaneous Blinking Fluorophores.

Hua Liu, Yingmei Cao, Yanan Deng, Lin Wei, Jinwu Yan, Lehui Xiao

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemical & biomedical imaging, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hua LiuCollege of Chemistry and Chemical Engineering, Central South University, Changsha 410083, China.
Yingmei CaoSchool of Biology and Biological Engineering, South China University of Technology, Guangzhou 510006, China.
Yanan DengCollege of Chemistry and Chemical Engineering, Central South University, Changsha 410083, China.
Lin WeiCollege of Chemistry and Chemical Engineering, Hunan Normal University, Changsha 410081, China.
Jinwu YanSchool of Biology and Biological Engineering, South China University of Technology, Guangzhou 510006, China.ORCID https://orcid.org/0000-0003-3014-0330
Lehui XiaoCollege of Chemistry and Chemical Engineering, Central South University, Changsha 410083, China.ORCID https://orcid.org/0000-0003-0522-2342

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Abnormal accumulation of intracellular and extracellular β-amyloid (Aβ) aggregates is closely related to the pathogenesis of Alzheimer's disease (AD). In this work, we use quinolinium derivatives with electron-rich aniline substituents as the skeletons to develop a set of spontaneous blinking fluorophores by the formation of long-lived radicals. These probes can target Aβ

Identifiers

PMID39473459
PMCPMC11504592

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.