Evidence map›Paper›PMID 39473245›Full record

ArticleCurrent cancer drug targets2025

Cardiovascular Mortality Risk Among Patients with Liver Cancer: A SEER Database Study.

Juan Li, Junyong Zhang, Song He

Abstract read
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In one paragraph

Article in Current cancer drug targets, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Juan LiThe Second Affiliated Hospital of Chongqing Medical University, Department of Gastroenterology, Chongqing, China.ORCID 0000-0003-3317-2709
Junyong ZhangThe Second Affiliated Hospital of Chongqing Medical University, Department of Urology, Chongqing, China.ORCID 0000-0001-7753-9520
Song HeThe Second Affiliated Hospital of Chongqing Medical University, Department of Gastroenterology, Chongqing, China.

Funding

Natural Science Foundation of Chongqing City CSTB2022NSCQ-MSX0879
6 · The paper itself

Abstract

Crucial for understanding liver cancer patients overall health outcomes. This research aimed to assess the CVM risk of them. METHODS AND MATERIALS: Data sourced from the Surveillance, Epidemiology, and End Results (SEER) database encompassing liver cancer diagnoses from 2000 to 2017 were utilized. The standardized mortality rate (SMR) was computed using general population reference data, and multivariate competing risk models were employed for analysis.

resultsAnalysis of 70,733 liver cancer patient records revealed 1,954 instances of CVM. The overall CVM SMR for liver cancer patients was 12.01 (95% CI: 11.48-12.55). Various demographic and clinical factors, including sex, race, age, year of diagnosis, pathological type, general stage, treatment modalities, and matrimonial status, emerged as liver cancer patients` independent predictors of CVM.

conclusionLiver cancer patients have a notably heightened susceptibility to cardiovascular mortality (CVM) in contrast to the general populace. It is imperative to promptly recognize high-risk subcategories and execute tailored cardiovascular interventions as crucial measures to bolster survival rates within this cohort of patients.

Indexed as

Cardiovascular DiseasesLiver NeoplasmsAdultAgedAged, 80 and overDatabases, FactualFemaleHumansMaleMiddle AgedRisk FactorsSEER ProgramSurvival RateUnited StatesCardiovascular mortalitycompeting risk regressioncumulative mortality curvescumulative mortality curves standardized mortality ratiosliver cancerSEER databasestandardized mortality ratios.

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.