Evidence map›Paper›PMID 39473186›Full record

ArticleJournal of cutaneous pathology2025

Line-Field Confocal Optical Coherence Tomography Imaging of Psoriasis With Histopathology Correlation.

Anna Elisa Verzì, Francesco Lacarrubba, Maria Letizia Musumeci, Rosario Caltabiano, Giuseppe Micali

Abstract read
In one paragraph

Article in Journal of cutaneous pathology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Anna Elisa VerzìDermatology Clinic, University of Catania, Catania, Italy.
Francesco LacarrubbaDermatology Clinic, University of Catania, Catania, Italy.
Maria Letizia MusumeciDermatology Clinic, University of Catania, Catania, Italy.
Rosario CaltabianoDepartment of Medical, Surgical Sciences and Advanced Technologies "G.F. Ingrassia", Anatomic Pathology, University of Catania, Catania, Italy.
Giuseppe MicaliDermatology Clinic, University of Catania, Catania, Italy.ORCID https://orcid.org/0000-0002-5157-3939

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Line-field confocal optical coherence tomography (LC-OCT) is a novel imaging technique for in vivo examination of the skin that has recently been introduced in the dermatologic armamentarium of non-invasive diagnostic tools. Its usefulness in the diagnosis and treatment monitoring of some neoplastic, inflammatory, and infectious skin conditions has been demonstrated. The aim of this study was to evaluate the LC-OCT features of psoriasis in a large number of psoriatic plaques along with their histopathologic correlation. In this retrospective study, the LC-OCT and the corresponding histopathologic images of 100 psoriatic plaques of the trunk, upper and lower arms from 60 patients that underwent both procedures were evaluated and correlated. The following microscopic findings, typical of plaque psoriasis, were observed at both LC-OCT and histopathology: hyperkeratosis, parakeratosis, acanthosis, papillomatosis and vascular changes, Munro microabscesses, and pustules of Kogoj. The LC-OCT findings perfectly matched with histopathology. Our study confirms the usefulness of this new imaging technique in the non-invasive visualization of the common diagnostic clues of psoriasis.

Indexed as

PsoriasisTomography, Optical CoherenceAdultAgedFemaleHumansMaleMiddle AgedRetrospective StudiesSkinAuspitz signhistopathologyLC‐OCTline‐field confocal optical coherence tomographypsoriasis

Identifiers

PMID39473186
PMCPMC11652119

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.