Evidence map›Paper›PMID 39473181›Full record

ArticleMolecular therapy : the journal of the American Society of Gene Therapy2024

Host RNA N

Na Wang, Qiaoling Liu, Bo Wang, Zhuo Yang, Siru Li, Ran Li, Xinyuan Liang, Jiayu Fan, Hui Wang, Zhen Sun and 8 more

Abstract read
In one paragraph

Article in Molecular therapy : the journal of the American Society of Gene Therapy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Nucleic acid modifications in self-nonself discrimination.Molecular therapy : the journal of the American Society of Gene Therapy · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Na WangInstitute of Cancer Stem Cell, DaLian Medical University, Dalian 116044, China.
Qiaoling LiuInstitute of Cancer Stem Cell, DaLian Medical University, Dalian 116044, China.
Bo WangDepartment of General Surgery, The Second Affiliated Hospital of DaLian Medical University, Dalian, China.
Zhuo YangDepartment of Gynecology, Cancer Hospital of DaLian University of Technology, Liaoning Cancer Hospital and Institute, Shenyang 110042, China.
Siru LiInstitute of Cancer Stem Cell, DaLian Medical University, Dalian 116044, China.
Ran LiInstitute of Cancer Stem Cell, DaLian Medical University, Dalian 116044, China.
Xinyuan LiangInstitute of Cancer Stem Cell, DaLian Medical University, Dalian 116044, China.
Jiayu FanInstitute of Cancer Stem Cell, DaLian Medical University, Dalian 116044, China.
Hui WangInstitute of Cancer Stem Cell, DaLian Medical University, Dalian 116044, China.
Zhen SunInstitute of Cancer Stem Cell, DaLian Medical University, Dalian 116044, China.
Ling DongInstitute of Cancer Stem Cell, DaLian Medical University, Dalian 116044, China.
Yueru HouInstitute of Cancer Stem Cell, DaLian Medical University, Dalian 116044, China.
Shengnan WangInstitute of Cancer Stem Cell, DaLian Medical University, Dalian 116044, China.
Chengli SongInstitute of Cancer Stem Cell, DaLian Medical University, Dalian 116044, China.
Yang WangInstitute of Cancer Stem Cell, DaLian Medical University, Dalian 116044, China.
Chunshan QuanDepartment of Bioengineering, College of Life Science, Dalian Minzu University, Dalian 116600, China.
Qingkai YangInstitute of Cancer Stem Cell, DaLian Medical University, Dalian 116044, China. Electronic address: yangqingkai@dmu.edu.cn.
Lina WangInstitute of Cancer Stem Cell, DaLian Medical University, Dalian 116044, China. Electronic address: li-nawang@dmu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Self-non-self discrimination is fundamental to life, thereby even microbes can apply DNA modifications to recognize non-self DNA. However, mammalian cytosolic DNA sensors indiscriminately bind DNA, necessitating specific mechanism(s) for self-non-self discrimination. Here, we show that mammalian RNA N

Indexed as

AdenosineDeoxyadenosinesAnimalsDNADNA, ViralHumansImmunologic SurveillanceMiceNucleotidyltransferasesRNAAdenosineDeoxyadenosinesDNADNA, ViralN-methyladenosineNucleotidyltransferasesRNAcyclic GMP-AMP synthaseDNA sensorimmune surveillanceN(6)-methyladenosineN(6)-methyldeoxyadenosinephase separation

Identifiers

PMID39473181
PMCPMC11638879

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.