Evidence map›Paper›PMID 39473163›Full record

ReviewChemphyschem : a European journal of chemical physics and physical chemistry2025

Radiation and DNA Origami Nanotechnology: Probing Structural Integrity at the Nanoscale.

João Ameixa, Leo Sala, Jaroslav Kocišek, Ilko Bald

Abstract readReview
In one paragraph

Review in Chemphyschem : a European journal of chemical physics and physical chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. CpG Methylation Protects DNA against Ionizing Radiation.The journal of physical chemistry. B · 2025
    Article
  5. Radiation and DNA Origami Nanotechnology: Probing Structural Integrity at the Nanoscale.Chemphyschem : a European journal of chemical physics and physical chemistry · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

João AmeixaHybrid Nanostructures, Institute of Chemistry, University of Potsdam, Karl-Liebknecht-Str. 24-25, Potsdam, 14476, Germany.
Leo SalaDynamics of Molecules and Clusters Department, J. Heyrovský Institute of Physical Chemistry of the CAS, Dolejškova 3, Prague, 182, 23, Czech Republic.ORCID 0000-0003-1091-4386
Jaroslav KocišekDynamics of Molecules and Clusters Department, J. Heyrovský Institute of Physical Chemistry of the CAS, Dolejškova 3, Prague, 182, 23, Czech Republic.
Ilko BaldHybrid Nanostructures, Institute of Chemistry, University of Potsdam, Karl-Liebknecht-Str. 24-25, Potsdam, 14476, Germany.ORCID 0000-0002-6683-5065

Funding

Czech Science Foundation 24-11503SGerman Research Foundation 450169704Ministry of Education, Youth, and Sports of the Czech Republic CZ.02.01.01/00/22_008/0004649
6 · The paper itself

Abstract

DNA nanotechnology has emerged as a groundbreaking field, using DNA as a scaffold to create nanostructures with customizable properties. These DNA nanostructures hold potential across various domains, from biomedicine to studying ionizing radiation-matter interactions at the nanoscale. This review explores how the various types of radiation, covering a spectrum from electrons and photons at sub-excitation energies to ion beams with high-linear energy transfer influence the structural integrity of DNA origami nanostructures. We discuss both direct effects and those mediated by secondary species like low-energy electrons (LEEs) and reactive oxygen species (ROS). Further we discuss the possibilities for applying radiation in modulating and controlling structural changes. Based on experimental insights, we identify current challenges in characterizing the responses of DNA nanostructures to radiation and outline further areas for investigation. This review not only clarifies the complex dynamics between ionizing radiation and DNA origami but also suggests new strategies for designing DNA nanostructures optimized for applications exposed to various qualities of ionizing radiation and their resulting byproducts.

Indexed as

DNANanostructuresNanotechnologyElectronsNucleic Acid ConformationRadiation, IonizingReactive Oxygen SpeciesDNAReactive Oxygen SpeciesDNA damageDNA structuresNanostructuresNanotechnology

Identifiers

PMID39473163
PMCPMC11747590

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.