Evidence map›Paper›PMID 39472996›Full record

SynthesisScandinavian journal of trauma, resuscitation and emergency medicine2024

Outcomes of odontoid fractures with associated cardiac arrest: retrospective bi-center case series and systematic literature review.

S F Schaible, S Häckel, N Rutsch, F C Aregger, S F Bigdon, V Schoenborn, I Broger, C E Albers, C Tinner

Abstract readSystematic ReviewMulticenter Study
In one paragraph

Synthesis in Scandinavian journal of trauma, resuscitation and emergency medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

S F SchaibleDepartment of Orthopaedic Surgery and Traumatology, University Hospital Bern, Inselspital, University of Bern, Freiburgstrasse 20, Bern, CH-3010, Switzerland.
S HäckelDepartment of Orthopaedic Surgery and Traumatology, University Hospital Bern, Inselspital, University of Bern, Freiburgstrasse 20, Bern, CH-3010, Switzerland.
N RutschDepartment of Orthopaedic Surgery and Traumatology, University Hospital Bern, Inselspital, University of Bern, Freiburgstrasse 20, Bern, CH-3010, Switzerland.
F C AreggerDepartment of Orthopaedic Surgery and Traumatology, University Hospital Bern, Inselspital, University of Bern, Freiburgstrasse 20, Bern, CH-3010, Switzerland.
S F BigdonDepartment of Orthopaedic Surgery and Traumatology, University Hospital Bern, Inselspital, University of Bern, Freiburgstrasse 20, Bern, CH-3010, Switzerland.
V SchoenbornDepartment of Orthopaedic Surgery and Traumatology, Cantonal Hospital Graubuenden, Loestrasse 99, Chur, CH-7000, Switzerland.
I BrogerDepartment of Orthopaedic Surgery and Traumatology, Cantonal Hospital Graubuenden, Loestrasse 99, Chur, CH-7000, Switzerland.
C E AlbersDepartment of Orthopaedic Surgery and Traumatology, University Hospital Bern, Inselspital, University of Bern, Freiburgstrasse 20, Bern, CH-3010, Switzerland.
C TinnerDepartment of Orthopaedic Surgery and Traumatology, University Hospital Bern, Inselspital, University of Bern, Freiburgstrasse 20, Bern, CH-3010, Switzerland. Christian.tinner@insel.ch.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOdontoid fractures from high-energy trauma are associated with significant morbidity and mortality, including spinal cord injury, neurological damage, and cardiac arrest. The literature on odontoid fractures leading to cardiac arrest is limited to isolated case reports. This study aims to conduct a retrospective bi-center case series and a systematic review of existing literature.

methodsWe conducted a retrospective bi-center case series on patients with odontoid fractures from high-energy trauma who experienced post-traumatic cardiac arrest with return of spontaneous circulation (ROSC) after CPR from two Level 1 Trauma Centers (2008-2024). The primary outcome was in-hospital mortality; secondary outcomes included epidemiological, pre-hospital, and in-hospital data, and CT and MRI findings. Additionally, we performed a systematic literature review to summarize existing evidence.

resultsThe study included 25 patients (mean age 71.1 ± 12.3 years, SD; 8 females). The mortality rate was 92% (23 patients). Median downtime before CPR was 5.0 min (IQR: 7.0), with CPR lasting 17.0 min (IQR: 13.0), primarily initiated by professionals (60%). All patients were quadriplegic. Type II Anderson d'Alonzo fractures were most common (88%), with all patients showing myelopathy on MRI. Only three patients (12%) underwent surgical intervention due to favorable prognosis. Our literature review identified seven case reports, with two patients surviving and one achieving full recovery.

conclusionsIn this case series, patients experiencing cardiac arrest after odontoid fractures exhibited high mortality rates despite comprehensive management at Level 1 trauma centers. Survivors faced significant and enduring morbidity.

Indexed as

Heart ArrestOdontoid ProcessSpinal FracturesAgedCardiopulmonary ResuscitationFemaleHospital MortalityHumansMaleMiddle AgedRetrospective StudiesTrauma CentersCervical injuriesHeart arrestResuscitationReviewSpinal injuries

Identifiers

PMID39472996
PMCPMC11523649

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.