ArticleScientific reports2024
Association of albumin-corrected anion gap with severe consciousness disorders and outcomes in ischemic stroke: a retrospective MIMIC analysis.
Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Article
- Association Between Serum Anion Gap and Risk of Postoperative Delirium in Patients Undergoing Gastric Surgery in ICU: A Retrospective Study From the MIMIC-IV Database.Anesthesiology research and practice · 2026Article
- The prognostic value of albumin-corrected anion gap for major adverse cardiac events in chronic kidney disease patients undergoing percutaneous coronary intervention.Frontiers in cardiovascular medicine · 2026Article
- Albumin-corrected anion gap and risk of mortality among US adults.Archives of public health = Archives belges de sante publique · 2025Article
- Prognostic value of albumin-corrected anion gap in severe chronic kidney disease with sepsis: association with mortality and clinical outcomes.European journal of medical research · 2025Article
- Albumin-corrected anion gap predicts acute kidney injury in critically ill patients with acute pancreatitis: a retrospective cohort study.BMC nephrology · 2025Article
- Serum albumin corrected anion gap levels are associated with poor prognosis in patients with acute ischemic stroke.Scientific reports · 2025Article
- Post-stroke mortality in ICU patients with serum glucose-potassium ratio: an analysis of MIMIC-IV database.Frontiers in neurology · 2025Article
- Article
- Article
- Complexities, Benefits, Risks, and Clinical Implications of Sodium Bicarbonate Administration in Critically Ill Patients: A State-of-the-Art Review.Journal of clinical medicine · 2024Review
- Article
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Authors and funding
3 authors.
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Abstract
The relationship between albumin-corrected anion gap (ACAG) and severe disorder of consciousness (SDOC), in-hospital mortality, and long-term mortality in patients with ischemic stroke (IS) remains unclear. This study investigates the association of ACAG with SDOC and other outcomes in IS using data from the MIMIC-IV database. A total of 2,379 IS patients were included, with a demographic breakdown showing 51% were male and an SDOC incidence of 16.4%. Analysis through Cox proportional hazards models indicated that ACAG is significantly associated with the risks of both SDOC and mortality. Additionally, restricted cubic spline(RCS) analysis suggested a nearly linear relationship between increasing ACAG levels and the incidence of SDOC. Kaplan-Meier curves demonstrated significant differences in the incidence rates of SDOC, in-hospital mortality, and long-term mortality across varying ACAG levels. The findings suggest that ACAG serves as an independent predictor for SDOC, in-hospital mortality, and long-term mortality in IS patients. Nonetheless, further prospective studies are needed to confirm these causal relationships.
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