Evidence map›Paper›PMID 39472491›Full record

ArticleScientific reports2024

A multiomics approach reveals RNA dynamics promote cellular sensitivity to DNA hypomethylation.

Alex Y Ge, Abolfazl Arab, Raymond Dai, Albertas Navickas, Lisa Fish, Kristle Garcia, Hosseinali Asgharian, Jackson Goudreau, Sean Lee, Kathryn Keenan and 5 more

Abstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Alex Y GeSchool of Medicine, University of California, San Francisco, San Francisco, CA, 94158, USA.
Abolfazl ArabArc Institute, Palo Alto, CA, 94304, USA.
Raymond DaiArc Institute, Palo Alto, CA, 94304, USA.
Albertas NavickasDepartment of Urology, University of California, San Francisco, San Francisco, CA, 94158, USA.
Lisa FishDepartment of Urology, University of California, San Francisco, San Francisco, CA, 94158, USA.
Kristle GarciaDepartment of Urology, University of California, San Francisco, San Francisco, CA, 94158, USA.
Hosseinali AsgharianDepartment of Urology, University of California, San Francisco, San Francisco, CA, 94158, USA.
Jackson GoudreauArc Institute, Palo Alto, CA, 94304, USA.
Sean LeeDepartment of Urology, University of California, San Francisco, San Francisco, CA, 94158, USA.
Kathryn KeenanTumor Cell Targeting Research Unit, Research, GSK, Collegeville, PA, 19426, USA.
Melissa B PappalardiTumor Cell Targeting Research Unit, Research, GSK, Collegeville, PA, 19426, USA.
Michael T McCabeTumor Cell Targeting Research Unit, Research, GSK, Collegeville, PA, 19426, USA.
Laralynne PrzybylaDepartment of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA, 94158, USA.
Hani GoodarziArc Institute, Palo Alto, CA, 94304, USA. Hani@arcinstitute.org.
Luke A GilbertArc Institute, Palo Alto, CA, 94304, USA. Luke@arcinstitute.org.

Funding

An antisense RNA-mediated regulatory program that drives cancer metastasisR01CA240984 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GOODARZI, HANI · 2019 to 2023
$2.5M
A GENETIC INTERACTION MAP OF THE HUMAN NUCLEUSDP2CA239597 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GILBERT, LUKE · 2018 to 2018
$2.4M
The RNA structural code underlying pathological regulation of RNA splicing in metastasisR01CA244634 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GOODARZI, HANI · 2021 to 2025
$1.8M
Illumina NovaSeq 6000 Sequencing SystemS10OD028511 · OD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CHOW, ERIC D · 2020 to 2020
$583k
NCI NIH HHS DP2 CA239597NCI NIH HHS R01 CA240984NCI NIH HHS R01 CA244634NIH HHS S10 OD028511
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID39472491
PMCPMC11522420

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.