Evidence map›Paper›PMID 39472410›Full record

ArticleClinical rheumatology2024

Postoperative complications in patients with Behçet's disease.

You Jin Jung, Eun Hye Park, Ju Yeon Kim, Eun Kyoung Lee, Yunhee Choi, Eun Bong Lee

Abstract read
In one paragraph

Article in Clinical rheumatology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
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2citing papers in PubMed
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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

You Jin Jung *Division of Rheumatology, Department of Internal Medicine, Seoul Metropolitan City Seoul Medical Center, Seoul, Republic of Korea.
Eun Hye Park *Division of Rheumatology, Department of Internal Medicine, Chung-Ang University College of Medicine, Seoul, Republic of Korea.ORCID http://orcid.org/0000-0002-6813-4182
Ju Yeon KimDivision of Rheumatology, Department of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea.
Eun Kyoung LeeDepartment of Ophthalmology, Seoul National University Hospital, Seoul, Republic of Korea.
Yunhee ChoiMedical Research Collaborating Center, Seoul National University Hospital, Seoul, Republic of Korea.
Eun Bong LeeDivision of Rheumatology, Department of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea. leb7616@snu.ac.kr.ORCID http://orcid.org/0000-0003-0703-1208

Funding

Ministry of Science, Technology and Space 2021R1A2C2004874
6 · The paper itself

Abstract

objectiveTo assess the proportion of postoperative complications of various surgeries in patients with Behçet's disease (BD) and compare the risk of surgical complications between BD patients and controls.

methodsWe analyzed 389 BD patients who underwent surgeries at Seoul National University Hospital between January 2003 and December 2019. Controls were 1:1 matched with BD patients based on age at surgery, sex, and type of surgery. Generalized estimating equation analyses were performed to compare the postoperative complications between BD patients and controls.

resultsAmong 632 surgeries in BD patients, 36 (5.7%) surgical site complications, including wound dehiscence (38.9%), bleeding (13.9%), infections (8.3%), anastomotic dehiscence (22.2%), and stricture (5.6%), occurred after median 12 days (IQR 7.8-22.0). Surgical site complications developed frequently after cardiac (33.3%) and vascular (22.2%) surgeries and rarely occurred after ophthalmic (1.5%) surgeries. Seventeen (2.7%) cases required reoperation within median 15 days (IQR 7.0-43.0). Four patients died within median 21 days (IQR 8.3-41.3 days). After adjustment for confounders, BD patients exhibited a significantly higher risk of surgical site complications (OR 3.4, 95% CI 1.4-8.0) and reoperation (OR 5.2, 95% CI 1.2-22.8) after cardiovascular surgery than controls. However, the risks of surgical site complications and reoperation after other types of surgery were similar in both groups.

conclusionsThe risk of postoperative complications varies according to the type of surgeries among BD patients. While cardiovascular surgeries result in higher perioperative complications in BD patients, ophthalmic surgeries show a safety profile similar to those in non-BD patients. Key Points • Patients with Behçet's disease exhibited an increased risk of surgical site complications and subsequent reoperations after cardiovascular surgery than controls. • The safety profile of ophthalmic surgery was comparable between patients with Behçet's disease and controls. • In patients with Behçet's disease, the risk of postoperative complications varies according to the type of surgery.

Indexed as

Behcet SyndromePostoperative ComplicationsAdultCase-Control StudiesFemaleHumansMaleMiddle AgedReoperationRetrospective StudiesRisk FactorsSurgical Wound DehiscenceBehçet’s diseaseCardiovascular surgeryOphthalmic surgeryPostoperative complicationReoperation

Identifiers

PMID39472410
PMCPMC11582265

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.