Evidence map›Paper›PMID 39472408›Full record

SynthesisHigh blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension2024

Efficacy and Safety of Ultrasound Renal Denervation on Office Blood Pressure of Patients with Resistant Arterial Hypertension: A Systematic Review and Meta-analysis.

Jose Guilherme Maia, Francinny Alves Kelly, Ocilio Ribeiro Gonçalves, Francisco Cezar Aquino de Moraes, Marcio Gonçalves de Sousa, Fernanda Marciano Consolim-Colombo

Abstract readSystematic ReviewMeta-Analysis
PubMed Publisher
In one paragraph

Synthesis in High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jose Guilherme MaiaFederal University of Amazonas, Afonso Pena St., 1053, Manaus, AM, 69020-160, Brazil. jose.maia0211@gmail.com.ORCID http://orcid.org/0009-0001-8646-4046
Francinny Alves KellyDante Pazzanese Cardiological Institute, São Paulo, São Paulo, Brazil.ORCID http://orcid.org/0000-0003-0706-6929
Ocilio Ribeiro GonçalvesFederal University of Piaui, Teresina, Piaui, Brazil.ORCID http://orcid.org/0009-0008-6103-8420
Francisco Cezar Aquino de MoraesFederal University of Para, Belem, Brazil.ORCID http://orcid.org/0000-0003-0623-8135
Marcio Gonçalves de SousaDante Pazzanese Cardiological Institute, São Paulo, São Paulo, Brazil.ORCID http://orcid.org/0000-0001-5460-5476
Fernanda Marciano Consolim-ColomboUniversity of Sao Paulo Heart Institute, São Paulo, Brazil.ORCID http://orcid.org/0000-0003-3220-019X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionResistant arterial hypertension (RAH) is one of the main causes of increased cardiovascular risk around the world. The benefits of ultrasound renal denervation (uRDN) as a non-invasive treatment are still not fully clear.

aimWe aim to demonstrate the efficacy of uRDN in reducing office blood pressure of patients in treatment for RAH.

methodsPubMed, Embase, and Cochrane were searched for randomized trials comparing uRDN to sham or medical control groups in RAH patients undergoing renal denervation. Mean Differences (MD) with 95% confidence intervals (CIs) were calculated, and I

resultsIt was included 5 studies with 709 patients, of which 395 (55.71%) received uRDN treatment and 314 (44.29%) in the sham group. Mean follow-up time ranged from 2 to 48 months and mean age ranged from 52.3 to 62 years. The uRDN decreased systolic blood pressure (SBP) and diastolic blood pressure (DBP) in all measures significantly, including reductions in Office SBP (MD - 4.459 mmHg; 95% CI - 7.710 to - 1.208; p = 0.007; I

conclusionsThis meta-analysis highlights uRDN's superiority over the sham group in controlling SBP and DBP in RAH. However, further studies are needed to fully understand the efficacy of uRDN procedure in the management of RAH.

Indexed as

Arterial PressureDrug ResistanceHypertensionKidneyRenal ArterySympathectomyAntihypertensive AgentsFemaleHumansMaleMiddle AgedOffice VisitsRandomized Controlled Trials as TopicTime FactorsTreatment OutcomeUltrasonic TherapyAntihypertensive AgentsDiastolic blood pressureResistant arterial hypertensionShamSystolic blood pressureUltrasound-based renal denervation

Identifiers

PMID39472408

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.