Evidence map›Paper›PMID 39472080›Full record

ArticleAnalytical chemistry2024

Label-Free SERS Sensors for Real-Time Monitoring of Tyrosine Phosphorylation.

Ailsa Geddis, Lorena Mendive-Tapia, Audreylia Sujantho, Erica Liu, Sarah McAughtrie, Richard Goodwin, Marc Vendrell, Colin J Campbell

Abstract read
In one paragraph

Article in Analytical chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ailsa GeddisEaStCHEM School of Chemistry, The University of Edinburgh, Edinburgh EH9 3FJ, U.K.
Lorena Mendive-TapiaCentre for Inflammation Research, The University of Edinburgh, Edinburgh EH16 4UU, U.K.
Audreylia SujanthoEaStCHEM School of Chemistry, The University of Edinburgh, Edinburgh EH9 3FJ, U.K.
Erica LiuEaStCHEM School of Chemistry, The University of Edinburgh, Edinburgh EH9 3FJ, U.K.
Sarah McAughtrieEaStCHEM School of Chemistry, The University of Edinburgh, Edinburgh EH9 3FJ, U.K.
Richard GoodwinClinical Pharmacology and Safety Sciences, Biopharmaceuticals R&D, AstraZeneca, Cambridge CB4 0WG, U.K.
Marc VendrellCentre for Inflammation Research, The University of Edinburgh, Edinburgh EH16 4UU, U.K.
Colin J CampbellEaStCHEM School of Chemistry, The University of Edinburgh, Edinburgh EH9 3FJ, U.K.ORCID 0000-0003-1917-6105

Funding

European Research Council
6 · The paper itself

Abstract

Dysregulation of receptor tyrosine kinases (RTKs) has been shown to correlate with cancer cell proliferation and drug resistance. Thus, monitoring the activity of RTKs at a chemical level could provide new biomedical insights and methods to assess the drug efficacy. However, direct monitoring of kinase activity is challenging and most commonly relies on

Indexed as

GoldMetal NanoparticlesReceptor Protein-Tyrosine KinasesSpectrum Analysis, RamanTyrosineAxl Receptor Tyrosine KinaseHumansPhosphorylationProto-Oncogene ProteinsTime FactorsAxl Receptor Tyrosine KinaseGoldProto-Oncogene ProteinsReceptor Protein-Tyrosine KinasesTyrosine

Identifiers

PMID39472080
PMCPMC11561882

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.