Evidence map›Paper›PMID 39472020›Full record

ArticleGenome research2025

Long-read RNA sequencing reveals allele-specific

Dayea Park, Can Cenik

Abstract read
In one paragraph

Article in Genome research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
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  8. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Dayea ParkDepartment of Molecular Biosciences, University of Texas at Austin, Austin, Texas 78712, USA.
Can CenikDepartment of Molecular Biosciences, University of Texas at Austin, Austin, Texas 78712, USA ccenik@austin.utexas.edu.ORCID 0000-0001-6370-0889

Funding

Single cell quantification of translation control in early mouse developmentR35GM150667 · NIGMS · UNIVERSITY OF TEXAS AT AUSTIN · PI Can Cenik · 2023 to 2026
$1.6M
Translational regulation of limb bud initiationR21HD110096 · NICHD · UNIVERSITY OF TEXAS AT AUSTIN · PI CENIK, CAN, VOKES, STEVEN ALEXANDER · 2022 to 2023
$436k
NICHD NIH HHS R21 HD110096NIGMS NIH HHS R35 GM150667
6 · The paper itself

Abstract

Long-read sequencing technology enables highly accurate detection of allele-specific RNA expression, providing insights into the effects of genetic variation on splicing and RNA abundance. Furthermore, the ability to directly sequence RNA enables the detection of RNA modifications in tandem with ascertaining the allelic origin of each molecule. Here, we leverage these advantages to determine allele-biased patterns of

Indexed as

AdenosineAllelesRNA, MessengerRNA Processing, Post-TranscriptionalSequence Analysis, RNAAnimalsHumansMiceAdenosineN-methyladenosineRNA, Messenger

Identifiers

PMID39472020
PMCPMC12047277

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.