Evidence map›Paper›PMID 39471986›Full record

ArticleInterventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences2024

"Chopperlysis": The effect of helicopter transport on reperfusion and outcomes in large vessel occlusion strokes.

Manisha Koneru, Jesse M Thon, Michael J Dubinski, Ana Leticia Fornari Caprara, Danielle C Brown, Zixin Yi, Omnea Elgendy, Jiyoun Ackerman, Mary Penckofer, Rosa Shi and 19 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

29 authors.

Manisha KoneruCooper Medical School of Rowan University, Camden, NJ, USA.ORCID 0000-0001-5012-6793
Jesse M ThonCooper Medical School of Rowan University, Camden, NJ, USA.
Michael J DubinskiCooper Medical School of Rowan University, Camden, NJ, USA.
Ana Leticia Fornari CapraraCooper Neurological Institute, Cooper University Health Care, Camden, NJ, USA.
Danielle C BrownCooper Medical School of Rowan University, Camden, NJ, USA.
Zixin YiCooper Medical School of Rowan University, Camden, NJ, USA.
Omnea ElgendyCooper Medical School of Rowan University, Camden, NJ, USA.
Jiyoun AckermanCooper Medical School of Rowan University, Camden, NJ, USA.
Mary PenckoferCooper Medical School of Rowan University, Camden, NJ, USA.
Rosa ShiCooper Medical School of Rowan University, Camden, NJ, USA.
Misa TrieuCooper Medical School of Rowan University, Camden, NJ, USA.
Lucas GarfinkelCooper Medical School of Rowan University, Camden, NJ, USA.
Tarun ThomasCooper Neurological Institute, Cooper University Health Care, Camden, NJ, USA.
Karan PatelCooper Medical School of Rowan University, Camden, NJ, USA.
Emma FrostCooper Neurological Institute, Cooper University Health Care, Camden, NJ, USA.
Abyson KalladanthyilCooper Medical School of Rowan University, Camden, NJ, USA.
Kenyon SprankleCooper Medical School of Rowan University, Camden, NJ, USA.
Renato OliveiraCooper Neurological Institute, Cooper University Health Care, Camden, NJ, USA.
Joshua SantucciCooper Neurological Institute, Cooper University Health Care, Camden, NJ, USA.
Ahmad A BalloutCooper Neurological Institute, Cooper University Health Care, Camden, NJ, USA.
James E SieglerCooper Neurological Institute, Cooper University Health Care, Camden, NJ, USA.
Hermann C SchumacherCooper Medical School of Rowan University, Camden, NJ, USA.
Khalid A HanafyCooper Medical School of Rowan University, Camden, NJ, USA.
Jane KhalifeCooper Medical School of Rowan University, Camden, NJ, USA.
Pratit D PatelCooper Medical School of Rowan University, Camden, NJ, USA.
Daniel A TonettiCooper Medical School of Rowan University, Camden, NJ, USA.
Ajith J ThomasCooper Medical School of Rowan University, Camden, NJ, USA.
Tudor G JovinCooper Medical School of Rowan University, Camden, NJ, USA.
Hamza A ShaikhCooper Medical School of Rowan University, Camden, NJ, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BackgroundIn large vessel occlusion (LVO) stroke patients transferred to a comprehensive stroke center for thrombectomy, spontaneous reperfusion may occur during transport, and anecdotally more frequently in patients transferred via helicopter than by ground. This pattern has been more often observed in conjunction with tenecteplase (TNK) treatment prior to helicopter transport. We aim to explore the "chopperlysis" effect-how helicopter transport, particularly with thrombolytics, may affect reperfusion and clinical outcomes.MethodsA single thrombectomy capable center (TCC) registry of stroke patients was retrospectively reviewed. Included LVO patients were those who had been transferred to the TCC and received a digital subtraction angiography (DSA) upon arrival. The outcomes were rates of spontaneous reperfusion, distal clot migration, and 90-day good functional outcome. Data were summarized, and endpoints were compared between patients stratified by transport method and/or TNK treatment.ResultsOf 270 patients included, helicopter transport was associated with a higher rate of spontaneous reperfusion, particularly among patients not treated with TNK (

Indexed as

helicopterIschemic strokereperfusiontenecteplasethrombectomy

Identifiers

PMID39471986
PMCPMC11559929

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.