Evidence map›Paper›PMID 39471779›Full record

ArticleAddictive behaviors2025

Cannabis use and associated longitudinal transitions in electronic nicotine delivery systems use among young adults in the United States.

Alexandra Loukas, C Nathan Marti, Melissa B Harrell, Keryn E Pasch, Anna V Wilkinson

Abstract read
In one paragraph

Article in Addictive behaviors, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Alexandra LoukasDepartment of Kinesiology & Health Education, University of Texas at Austin, 2700 San Jacinto Blvd. D3700, Austin, TX 78712, USA. Electronic address: alexandra.loukas@austin.utexas.edu.
C Nathan MartiDepartment of Kinesiology & Health Education, University of Texas at Austin, 2700 San Jacinto Blvd. D3700, Austin, TX 78712, USA.
Melissa B HarrellDepartment of Epidemiology, UTHealth Houston School of Public Health, 1836 San Jacinto, Austin, TX 78701, USA.
Keryn E PaschDepartment of Kinesiology & Health Education, University of Texas at Austin, 2700 San Jacinto Blvd. D3700, Austin, TX 78712, USA.
Anna V WilkinsonDepartment of Epidemiology, UTHealth Houston School of Public Health, 1836 San Jacinto, Austin, TX 78701, USA.

Funding

Training & Education Core p335-350P50CA180906 · NCI · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI PERRY, CHERYL LEE · 2013 to 2017
$19.7M
ENDS use trajectories from adolescence through young adulthood: A longitudinal study of risk factors and profilesR01CA239097 · NCI · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI HARRELL, MELISSA BLYTHE · 2019 to 2023
$3.3M
Social Media, Acculturation and E-cigarette Use among Mexican American College Students in South TexasR01MD017280 · NIMHD · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI ALEXANDRA LOUKAS, Anna Victoria Wilkinson · 2022 to 2026
$3.3M
Depressive Symptoms and Tobacco Use Trajectories and Transitions across Young AdulthoodR01CA249883 · NCI · UNIVERSITY OF TEXAS AT AUSTIN · PI LOUKAS, ALEXANDRA · 2020 to 2022
$1.2M
NCI NIH HHS P50 CA180906NCI NIH HHS R01 CA239097NCI NIH HHS R01 CA249883NIMHD NIH HHS R01 MD017280
6 · The paper itself

Abstract

objectiveCannabis is increasingly the first substance used by young people and research indicates that cannabis use may precede the onset of tobacco use. Little is known, however, about the role of cannabis use in stages of electronic nicotine delivery systems (ENDS) uptake and progression across young adulthood. This study examined the associations between past 30-day (P30D) cannabis use frequency and transitions in ENDS use among young adults.

methods5,018 18-29-year-olds (64.2% female) were recruited from 24 Texas colleges to participate in a multi-wave study across a 4.5-year period from 2014 to 2019. A continuous time, multi-state Markov model was used to assess associations between P30D cannabis use frequency and three ENDS use transitions, spanning at least six months 1) never to P30D use (initiation); 2) P30D to non-P30D use (desistance); and 3) non-P30D to P30D use (re-uptake). The model also included socio-demographic and time-varying intrapersonal (other tobacco use, alcohol use, sensation seeking, depressive symptoms) and interpersonal (peer ENDS use) confounding factors.

resultsPast 30-day cannabis use frequency was associated with an increased probability of ENDS initiation and decreased probability of desistance in the model adjusted for socio-demographic and confounding factors. Past 30-day cannabis use frequency was not associated with an increased probability of ENDS re-uptake in the adjusted model.

conclusionsCannabis use is associated with the uptake and continuation of ENDS use. Findings are concerning given that the most popular ENDS devices used by young adults contain high concentrations of nicotine that increase the risk for nicotine dependence and lifelong use.

Indexed as

Electronic Nicotine Delivery SystemsMarijuana UseVapingAdolescentAdultFemaleHumansLongitudinal StudiesMaleStudentsTexasUnited StatesUniversitiesYoung AdultEmerging adulthoodLongitudinal transitionsMarijuana useNatural history of substance useStages of e-cigarette useTobacco use

Identifiers

PMID39471779
PMCPMC12199531

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.