Evidence map›Paper›PMID 39471521›Full record

ArticleThe American journal of tropical medicine and hygiene2025

The Transformative Impact of the African Cohort Study (AFRICOS) Toward Reaching HIV 95-95-95 Goals in Sub-Saharan Africa.

Neha Shah, Trevor A Crowell, Jaclyn Hern, Victor Anyebe, Emmanuel Bahemana, Hannah Kibuuka, Valentine Singoei, Jonah Maswai, Ajay Parikh, Emma R Duff and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Neha ShahU.S. Military HIV Research Program, Center of Infectious Disease Research, Walter Reed Army Institute of Research, Silver Spring, Maryland.
Trevor A CrowellU.S. Military HIV Research Program, Center of Infectious Disease Research, Walter Reed Army Institute of Research, Silver Spring, Maryland.
Jaclyn HernU.S. Military HIV Research Program, Center of Infectious Disease Research, Walter Reed Army Institute of Research, Silver Spring, Maryland.
Victor AnyebeU.S. Military HIV Research Program, Walter Reed Army Institute of Research Africa, Abuja, Nigeria.
Emmanuel BahemanaU.S. Military HIV Research Program, Walter Reed Army Institute of Research Africa, Mbeya, Tanzania.
Hannah KibuukaMakerere University Walter Reed Project, Kampala, Uganda.
Valentine SingoeiU.S. Military HIV Research Program, Walter Reed Army Institute of Research, Walter Reed Army Institute of Research Africa, Kisumu, Kenya.
Jonah MaswaiU.S. Military HIV Research Program, Walter Reed Army Institute of Research, Walter Reed Army Institute of Research Africa, Kericho, Kenya.
Ajay ParikhU.S. Military HIV Research Program, Center of Infectious Disease Research, Walter Reed Army Institute of Research, Silver Spring, Maryland.
Emma R DuffU.S. Military HIV Research Program, Center of Infectious Disease Research, Walter Reed Army Institute of Research, Silver Spring, Maryland.
Joseph Sean CavanaughU.S. Military HIV Research Program, Center of Infectious Disease Research, Walter Reed Army Institute of Research, Silver Spring, Maryland.
Matthew L RomoU.S. Military HIV Research Program, Center of Infectious Disease Research, Walter Reed Army Institute of Research, Silver Spring, Maryland.
Julie A AkeU.S. Military HIV Research Program, Center of Infectious Disease Research, Walter Reed Army Institute of Research, Silver Spring, Maryland.
Michael J A ReidBureau of Global Health Security and Diplomacy, President's Emergency Plan for AIDS Relief, Washington, District of Columbia.
Amb John N NkengasongBureau of Global Health Security and Diplomacy, President's Emergency Plan for AIDS Relief, Washington, District of Columbia.
AFRICOS Study Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Over the last 20 years, the U.S. President's Emergency Plan for AIDS Relief (PEPFAR) has rapidly expanded and made remarkable progress toward the UNAIDS 95-95-95 targets to end the HIV epidemic. Nevertheless, HIV continues to pose a significant health challenge globally, with a particular impact on the African continent. Funded by PEPFAR, the African Cohort Study (AFRICOS) has served as a monitoring and evaluation tool for PEPFAR to help guide HIV policy and PEPFAR programming for the last 10 years since its inception and offers a compelling example of how PEPFAR's investment in science continues to reap dividends. This paper details and critically reviews the transformative research AFRICOS has had on helping to end the HIV epidemic as a public health threat by 2030.

Indexed as

HIV InfectionsAfrica South of the SaharaCohort StudiesEpidemicsGoalsHumansInternational Cooperation

Identifiers

PMID39471521
PMCPMC11720777

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.