Evidence map›Paper›PMID 39471503›Full record

SynthesisThe American journal of tropical medicine and hygiene2025

The Epidemiological Impact of Dengue in Colombia: A Systematic Review.

Alfonso J Rodríguez-Morales, Eduardo López-Medina, Iván Arboleda, Jaime A Cardona-Ospina, Jaime E Castellanos, Álvaro A Faccini-Martínez, Elaine Gallagher, Riona Hanley, Pio Lopez, Salim Mattar and 7 more

Abstract readSystematic Review
In one paragraph

Synthesis in The American journal of tropical medicine and hygiene, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Review
  2. Article
  3. Observational
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Observational
  10. Article
  11. Article
  12. Review
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Alfonso J Rodríguez-MoralesGrupo de Investigación Biomedicina, Faculty of Medicine, Fundación Universitaria Autónoma de las Américas-Institución Universitaria Visión de las Américas, Pereira, Colombia.
Eduardo López-MedinaColombian Association of Infectious Diseases (ACIN), Bogotá, Colombia.
Iván ArboledaBaxalta Colombia SAS, (Takeda), Bogotá, Colombia.
Jaime A Cardona-OspinaGrupo de Investigación Biomedicina, Faculty of Medicine, Fundación Universitaria Autónoma de las Américas-Institución Universitaria Visión de las Américas, Pereira, Colombia.
Jaime E CastellanosColombian Association of Infectious Diseases (ACIN), Bogotá, Colombia.
Álvaro A Faccini-MartínezServicio de Infectología, Hospital Militar Central, Bogotá, Colombia.
Elaine GallagherTakeda Pharmaceuticals International AG, Zurich, Switzerland.
Riona HanleyTakeda Pharmaceuticals International AG, Zurich, Switzerland.
Pio LopezColombian Association of Infectious Diseases (ACIN), Bogotá, Colombia.
Salim MattarColombian Association of Infectious Diseases (ACIN), Bogotá, Colombia.
Carlos Eduardo PérezColombian Association of Infectious Diseases (ACIN), Bogotá, Colombia.
Randee KastnerTakeda Pharmaceuticals International AG, Zurich, Switzerland.
Humberto ReynalesCentro de Atención e Investigación Médica - CAIMED, Chía, Colombia.
Fernando RossoFundación Valle del Lili, Infectious Diseases Service, Cali, Colombia.
Jing ShenInstituto de Investigaciones Biológicas del Trópico, Universidad de Córdoba, Montería, Colombia.
Wilmer E Villamil-GómezColombian Association of Infectious Diseases (ACIN), Bogotá, Colombia.
Marcela FuquenColombian Association of Infectious Diseases (ACIN), Bogotá, Colombia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dengue is the most important viral vector-borne disease in the tropics, with Colombia being one of the most affected countries. In this context, it is essential to identify and synthesize the existing evidence on the epidemiology of dengue in Colombia. A systematic review (PROSPERO CRD42021257985) was conducted by searching for epidemiological data in populations with suspected or confirmed dengue in Colombia from 2012 to 2020. We searched PubMed, EMBASE, the Cochrane Library, the LILACS, and SciELO databases, and 104 publications out of 1,234 records were selected. The dengue annual incidence rate varied through the years without a clear trend. The lowest annual incidence rate was observed in 2017 (90.7 per 100,000 population) and the highest in 2013 (476.2 per 100,000 population). The proportion of severe cases in the same period ranged between 0.89% in 2016 and 2.7% in 2012. The four dengue virus (DENV) serotypes co-circulated in the country, and DENV-2 was the predominant serotype. Fifty percent of dengue cases occurred in people under 20 years, and those between 5 and 14 years had the highest incidence rate. The mortality rate for all dengue cases ranged from 0.07% in 2020 to 0.16% in 2012 and 2015. In conclusion, dengue is a hyperendemic disease in Colombia with the circulation of four serotypes. New strategies must be implemented to prevent the contagion and impact of the disease on the population at risk.

Indexed as

DengueDengue VirusAdolescentColombiaHumansIncidenceSerogroup

Identifiers

PMID39471503
PMCPMC11720756

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.