SynthesisThe American journal of gastroenterology2024
Social Disadvantage and Disparities in Chronic Liver Disease: A Systematic Review.
Synthesis in The American journal of gastroenterology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed.
- The Cirrhosis Medical Home: A Pilot Randomized Trial of a Collaborative Care Model for Patients With Decompensated Cirrhosis.Clinical and translational gastroenterology · 2026Trial
- Social and Functional Risk Patterns and All-Cause Mortality Among US Adults with Chronic Liver Disease.Medical sciences (Basel, Switzerland) · 2026Article
- Reduced wait times for hepatology referrals in a prospective quality improvement initiative.Hepatology communications · 2026Article
- Role of social determinants and outcomes of patients with alcohol-associated liver disease referred for early liver transplantation: A multicenter analysis.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2026Article
- Spontaneous Recovery and Mortality in Patients With ALD Referred for Early Liver Transplantation.The American journal of gastroenterology · 2026Article
- Barriers to Medical Care Are Frequently Reported by Patients With Cirrhosis.Alimentary pharmacology & therapeutics · 2026Article
- Excess mortality from cirrhosis by neighbourhood deprivation, aetiology, and clinical presentation: a Swedish register-based cohort study.EClinicalMedicine · 2026Article
- Measuring health inequalities in liver transplantation: a systematic review of deprivation scores for survival in end-stage liver disease.BMJ public health · 2026Article
- The shifting burden of gastrointestinal and liver diseases in Southeast Asia and effective control strategies.Asian biomedicine : research, reviews and news · 2025Article
- "The alcohol-harm paradox": Understanding socioeconomic inequalities in liver disease.JHEP reports : innovation in hepatology · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Funding
Abstract
introductionSocial determinants of health (SDOH) may impact chronic liver disease (CLD) outcomes but are not clearly understood. We conducted a systematic review to describe the associations of SDOH with mortality, hospitalizations, and readmissions among patients with CLD.
methodsThis review was registered (PROSPERO ID: CRD42022346654) and identified articles through MEDLINE, Embase, Cochrane Library, and Scopus databases. The review included studies that reported SDOH characteristics within the domains of economic stability, healthcare access, education, social and community context, and the neighborhood-built environment. Associated outcomes of interest were mortality, hospitalizations, or readmissions. The Cochrane Risk of Bias in Nonrandomized Studies for Exposure was used to assess study quality and risk of bias.
resultsA total of 5,205 abstracts were screened, 60 articles underwent full-text review, and 27 articles were included in the final review. Poor economic stability, healthcare access, social support, and household/environmental conditions were associated with higher mortality and hospital readmissions among patients with CLD. Increasing distance (≥25 miles away) from a liver transplantation center was associated with higher mortality, despite increasing access to the liver transplantation waitlist. When assessing the overall risk of bias among included studies, most had "some concern" (N = 13, 48.1%) or "high risk" (N = 11, 40.7%), whereas a minority had "very high risk" (N = 3, 11.1%). No studies were categorized as "low risk." DISCUSSION: Unfavorable SDOH were associated with increased mortality and hospital readmissions among patients with CLD. Rigorous empirical research is needed to identify evidence-based strategies that aim to mitigate disparities among vulnerable populations.
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Registered trials
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