Evidence map›Paper›PMID 39471328›Full record

ArticleAmerican journal of respiratory cell and molecular biology2025

Guarding the Endothelium: SOX17's Crucial Role in Pulmonary Hypertension.

Xinyi Zhang, Zhiyu Dai

Abstract readEditorialComment
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of respiratory cell and molecular biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. SOX17 in pulmonary arterial hypertension: from development to clinical phenotype.European respiratory review : an official journal of the European Respiratory Society · 2025
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Xinyi ZhangDepartment of Medicine Division of Pulmonary and Critical Care Medicine Washington University School of Medicine in St. Louis St. Louis, Missouri.
Zhiyu DaiDepartment of Medicine Division of Pulmonary and Critical Care Medicine Washington University School of Medicine in St. Louis St. Louis, Missouri.ORCID 0000-0002-2945-7923

Funding

Novel alveolar mechanisms of hypoxemia in hepatopulmonary syndromeR01HL169509 · NHLBI · UNIVERSITY OF ARIZONA · PI Zhiyu Dai, MICHAEL B FALLON · 2023 to 2026
$3.0M
General Capillary to Arterial Endothelial Cell Transition in Pulmonary ArterialHypertensionR01HL170096 · NHLBI · WASHINGTON UNIVERSITY · PI Zhiyu Dai · 2023 to 2026
$2.9M
Role of Endothelial SOX17 Deficiency in the Pathogenesis of Pulmonary HypertensionR01HL158596 · NHLBI · WASHINGTON UNIVERSITY · PI Zhiyu Dai · 2022 to 2026
$2.3M
Fatty acid-binding proteins sustain endothelial glycolysis and arterial programming in pulmonary arterial hypertensionR01HL162794 · NHLBI · WASHINGTON UNIVERSITY · PI Zhiyu Dai · 2023 to 2026
$2.3M
NHLBI NIH HHS R01 HL158596NHLBI NIH HHS R01HL158596NHLBI NIH HHS R01 HL162794NHLBI NIH HHS R01HL162794NHLBI NIH HHS R01 HL169509NHLBI NIH HHS R01HL169509NHLBI NIH HHS R01 HL170096NHLBI NIH HHS R01HL170096
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID39471328
PMCPMC12005006

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.