Evidence map›Paper›PMID 39471283›Full record

ArticleACS applied materials & interfaces2025

Investigating T Cell Immune Dynamics and IL-6's Duality in a Microfluidic Lung Tumor Model.

Parvaneh Sardarabadi, Kang-Yun Lee, Wei-Lun Sun, Amir Asri Kojabad, Cheng-Hsien Liu

Abstract read
In one paragraph

Article in ACS applied materials & interfaces, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Parvaneh SardarabadiInstitute of Nanoengineering and Microsystems, National Tsing Hua University, Hsinchu 30044, Taiwan, R.O.C.ORCID 0000-0001-7135-7101
Kang-Yun LeeDivision of Pulmonary Medicine, Department of Internal Medicine, Shuang Ho Hospital, Taipei Medical University, New Taipei City 235, Taiwan, R.O.C.
Wei-Lun SunPythia Biotech LTD., New Taipei City 23561, Taiwan, R.O.C.
Amir Asri KojabadDepartment of Hematology, School of Allied Medical Sciences, Iran University of Medical Sciences, Tehran 14535, Iran.ORCID 0000-0002-4036-9879
Cheng-Hsien LiuInstitute of Nanoengineering and Microsystems, National Tsing Hua University, Hsinchu 30044, Taiwan, R.O.C.ORCID 0000-0003-1882-3892

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Interleukin 6 (IL-6), produced by immune cells, is crucial in promoting T cell trafficking to infection and inflammation sites, influencing various physiological and pathological processes. Concentrations of IL-6 and other cytokines and chemokines can influence T cell differentiation and activation. Understanding the dual faces of IL-6 within the tumor microenvironment is crucial to understanding its role. A flow-based microsystem was designed to investigate CD4

Indexed as

CD4-Positive T-LymphocytesInterleukin-6Lung NeoplasmsT-LymphocytesA549 CellsCell MovementHumansJurkat CellsLymphocyte ActivationTumor MicroenvironmentIL6 protein, humanInterleukin-6chemokineimmune cellsinterleukin 6microfluidic biochiptumor microenvironment

Identifiers

PMID39471283
PMCPMC11758792

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.