Evidence map›Paper›PMID 39471227›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2024

A novel

Kristin A Fluke, Nan Dai, Eric J Wolf, Ryan T Fuchs, P Shing Ho, Victoria Talbott, Liam Elkins, Yueh-Lin Tsai, Jackson Schiltz, Hallie P Febvre and 4 more

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. International journal of molecular sciences · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Kristin A FlukeCell and Molecular Biology Graduate Program, Colorado State University, Fort Collins, CO 80523.ORCID 0000-0002-3398-3184
Nan DaiNew England Biolabs Inc., Beverly, MA 01915.
Eric J WolfNew England Biolabs Inc., Beverly, MA 01915.
Ryan T FuchsNew England Biolabs Inc., Beverly, MA 01915.ORCID 0000-0001-8238-6442
P Shing HoDepartment of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, CO 80523.ORCID 0000-0002-8082-4311
Victoria TalbottCell and Molecular Biology Graduate Program, Colorado State University, Fort Collins, CO 80523.ORCID 0009-0000-6078-997X
Liam ElkinsCell and Molecular Biology Graduate Program, Colorado State University, Fort Collins, CO 80523.
Yueh-Lin TsaiNew England Biolabs Inc., Beverly, MA 01915.
Jackson SchiltzDepartment of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, CO 80523.
Hallie P FebvreDepartment of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, CO 80523.ORCID 0009-0004-9443-616X
Ryan CzarnyDepartment of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, CO 80523.
G Brett RobbNew England Biolabs Inc., Beverly, MA 01915.ORCID 0000-0002-2382-2256
Ivan R CorrêaNew England Biolabs Inc., Beverly, MA 01915.ORCID 0000-0002-3169-6878
Thomas J SantangeloCell and Molecular Biology Graduate Program, Colorado State University, Fort Collins, CO 80523.ORCID 0000-0003-4559-3244

Funding

Predoctoral Training in Quantitative Cell & Molecular BiologyT32GM132057 · NIGMS · COLORADO STATE UNIVERSITY · PI Karen Marie Dobos, Brian Munsky · 2019 to 2026
$2.9M
Regulation of Archaeal TranscriptionR35GM143963 · NIGMS · COLORADO STATE UNIVERSITY · PI Thomas James Santangelo · 2022 to 2026
$1.8M
HHS | NIH (NIH) GM132057HHS | NIH (NIH) R35-GM143963New England Biolabs (NEB) Not applicableNIGMS NIH HHS R35 GM143963NIGMS NIH HHS T32 GM132057NSF (NSF) 2022065NSF (NSF) MCB-2124202
6 · The paper itself

Abstract

Ribosome structure and activity are challenged at high temperatures, often demanding modifications to ribosomal RNAs (rRNAs) to retain translation fidelity. LC-MS/MS, bisulfite-sequencing, and high-resolution cryo-EM structures of the archaeal ribosome identified an RNA modification,

Indexed as

CytidineRibosomesArchaeaArchaeal ProteinsMethyltransferasesPhylogenyRNA, ArchaealRNA, Ribosomal, 16SArchaeal ProteinsCytidineMethyltransferasesRNA, ArchaealRNA, Ribosomal, 16SarchaeaepitranscriptomehyperthermophileN4,N4-dimethylcytidineRNA modifications

Identifiers

PMID39471227
PMCPMC11551388

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.