Evidence map›Paper›PMID 39471219›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2024

Zhihua Zhang, Ran Yu, Qiuwen Shi, Zhi-Jing Wu, Qingchun Li, Jian Mu, Biaobang Chen, Juanzi Shi, Renmin Ni, Ling Wu and 9 more

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Quercetin ameliorates aflatoxin BJournal of animal science and biotechnology · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. hnRNPU Safeguards Oocyte Development and Female Fertility via Regulation of Alternative Splicing.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Review
  16. Abnormalities of Oocyte Maturation: Mechanisms and Implications.International journal of molecular sciences · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Zhihua Zhang *Institute of Pediatrics, Children's Hospital of Fudan University, The Institutes of Biomedical Sciences, State Key Laboratory of Genetic Engineering, Fudan University, Shanghai 200032, China.ORCID 0000-0002-4725-883X
Ran Yu *Institute of Pediatrics, Children's Hospital of Fudan University, The Institutes of Biomedical Sciences, State Key Laboratory of Genetic Engineering, Fudan University, Shanghai 200032, China.ORCID 0009-0008-1017-7332
Qiuwen Shi *Reproductive Medicine Center, The Third Affiliated Hospital, Guangxi Medical University, Nanning 530031, Guangxi, China.
Zhi-Jing Wu *The State Key Laboratory of Molecular Biology, Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai 200031, China.ORCID 0000-0002-9203-0252
Qingchun Li *Department of Reproductive Medicine, Binzhou Medical University Hospital, Binzhou 256603, China.ORCID 0009-0007-0311-3173
Jian Mu *Institute of Pediatrics, Children's Hospital of Fudan University, The Institutes of Biomedical Sciences, State Key Laboratory of Genetic Engineering, Fudan University, Shanghai 200032, China.ORCID 0000-0001-6923-6415
Biaobang ChenKey Lab of Reproduction Regulation (Shanghai Institute for Biomedical and Pharmaceutical Technologies), National Health Commission of the People's Republic of China, Shanghai 200032, China.ORCID 0000-0002-9921-2155
Juanzi ShiReproductive Medicine Center, Northwest Women's and Children's Hospital, Xi'an 710069, China.ORCID 0000-0003-4261-6818
Renmin NiDepartment of Reproductive Medicine, Kunming Angel Women's and Children's Hospital, Kunming 650031, Yunnan, China.ORCID 0009-0006-0004-4451
Ling WuDepartment of Assisted Reproduction, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200011, China.ORCID 0000-0001-9217-9412
Qiaoli LiInstitute of Pediatrics, Children's Hospital of Fudan University, The Institutes of Biomedical Sciences, State Key Laboratory of Genetic Engineering, Fudan University, Shanghai 200032, China.ORCID 0000-0002-5258-3346
Jing FuShanghai Ji Ai Genetics and In Vitro Fertilization Institute, Obstetrics and Gynecology Hospital, Fudan University, Shanghai 200011, China.
Rong LiReproductive Medicine Center, The Third Affiliated Hospital, Guangxi Medical University, Nanning 530031, Guangxi, China.
Xiaoxi SunShanghai Ji Ai Genetics and In Vitro Fertilization Institute, Obstetrics and Gynecology Hospital, Fudan University, Shanghai 200011, China.ORCID 0000-0002-3366-5821
Jiucun WangState Key Laboratory of Genetic Engineering, School of Life Sciences, Human Phenome Institute, Zhangjiang Fudan International Innovation Center, Fudan University, Shanghai 200438, China.
Lin HeBio-X Center, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders, Ministry of Education, Shanghai Jiao Tong University, Shanghai 200030, China.
Yanping KuangDepartment of Assisted Reproduction, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200011, China.ORCID 0000-0003-2985-5793
Qing SangInstitute of Pediatrics, Children's Hospital of Fudan University, The Institutes of Biomedical Sciences, State Key Laboratory of Genetic Engineering, Fudan University, Shanghai 200032, China.ORCID 0000-0002-9895-1394
Lei WangInstitute of Pediatrics, Children's Hospital of Fudan University, The Institutes of Biomedical Sciences, State Key Laboratory of Genetic Engineering, Fudan University, Shanghai 200032, China.ORCID 0000-0002-3400-0434

Funding

The National Natural Key R&D Program of China 2021YFC2700100the National Natural Science Foundation of China 82288102 82325021 32130029 82171643 82371662 82001538
6 · The paper itself

Abstract

Mitochondria play diverse roles in mammalian physiology. The architecture, activity, and physiological functions of mitochondria in oocytes are largely different from those in somatic cells, but the mitochondrial proteins related to oocyte quality and reproductive longevity remain largely unknown. Here, using whole-exome sequencing data from 1,024 women (characterized by oocyte maturation arrest and degenerated or morphologically abnormal oocytes) and 2,868 healthy controls, we performed a population and gene-based burden test for mitochondrial genes and identified a candidate gene, cytochrome c oxidase assembly protein 15 (

Indexed as

FerroptosisMitochondriaOocytesAdultExome SequencingFemaleHeLa CellsHumansInfertility, FemaleMitochondrial ProteinsReactive Oxygen SpeciesSaccharomyces cerevisiaeMitochondrial ProteinsReactive Oxygen SpeciesCOX15 deficiencyfemale infertilityferroptosismitochondrial disordersoocyte defects

Identifiers

PMID39471219
PMCPMC11551447

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.