Evidence map›Paper›PMID 39471216›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2024

Is stochastic thermodynamics the key to understanding the energy costs of computation?

David H Wolpert, Jan Korbel, Christopher W Lynn, Farita Tasnim, Joshua A Grochow, Gülce Kardeş, James B Aimone, Vijay Balasubramanian, Eric De Giuli, David Doty and 9 more

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Identification and quantification of irreversibility in stochastic systems.Physical chemistry chemical physics : PCCP · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Landauer's Principle: Past, Present and Future.Entropy (Basel, Switzerland) · 2025
    Article
  11. Maximizing Free Energy Gain.Entropy (Basel, Switzerland) · 2025
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

David H WolpertSanta Fe Institute, Santa Fe, NM 87501.ORCID 0000-0003-3105-2869
Jan KorbelComplexity Science Hub Vienna, Vienna 1080, Austria.ORCID 0000-0002-5371-5320
Christopher W LynnCenter for the Physics of Biological Function, Princeton University, Princeton, NJ 08544.
Farita TasnimBrilliant.org, New York, NY 10036.
Joshua A GrochowDepartment of Computer Science, University of Colorado Boulder, Boulder, CO 80309.ORCID 0000-0002-6466-0476
Gülce KardeşSanta Fe Institute, Santa Fe, NM 87501.
James B AimoneSandia National Laboratories, Albuquerque, NM 87185.
Vijay BalasubramanianSanta Fe Institute, Santa Fe, NM 87501.ORCID 0000-0002-6497-3819
Eric De GiuliDepartment of Physics, Toronto Metropolitan University, M5B 2K3, Toronto, ON, Canada.ORCID 0000-0001-7267-6526
David DotyDepartment of Computer Science, University of California, 95616, Davis, CA.ORCID 0000-0002-3922-172X
Nahuel FreitasDepartment of Physics, University of Buenos Aires, C1053, Buenos Aires, Argentina.
Matteo MarsiliThe Abdus Salam International Centre for Theoretical Physics, Trieste 34151, Italy.ORCID 0000-0001-9437-6989
Thomas E OuldridgeDepartment of Bioengineering, Imperial College London, SW7 2AZ, London, United Kingdom.ORCID 0000-0001-8114-8602
Andréa W RichaSchool of Computing and Augmented Intelligence, Arizona State University, Tempe, AZ 85287.ORCID 0000-0003-3592-3756
Paul RiechersSchool of Physical and Mathematical Sciences, Nanyang Quantum Hub, Nanyang Technological University, Singapore 639798, Singapore.ORCID 0000-0002-0135-3778
Édgar RoldánThe Abdus Salam International Centre for Theoretical Physics, Trieste 34151, Italy.
Brenda RubensteinDepartment of Chemistry, Brown University, Providence, RI 02912.
Zoltan ToroczkaiDepartment of Physics and Astronomy, University of Notre Dame, Notre Dame, IN 46556.ORCID 0000-0002-6602-2849
Joseph ParadisoMassachusetts Institute of Technology Media Lab, Massachusetts Institute of Technology, Cambridge, MA 02139.ORCID 0000-0002-0719-7104

Funding

Austrian Science Fund (FWF) P34994Ministero dell'Università e della Ricerca (MUR) PE0000023-NQSTNational Science Foundation (NSF) CCF-2047756National Science Foundation (NSF) CCF-2221345NTT Research (NTT Research, Inc.) 0000
6 · The paper itself

Abstract

The relationship between the thermodynamic and computational properties of physical systems has been a major theoretical interest since at least the 19th century. It has also become of increasing practical importance over the last half-century as the energetic cost of digital devices has exploded. Importantly, real-world computers obey multiple physical constraints on how they work, which affects their thermodynamic properties. Moreover, many of these constraints apply to both naturally occurring computers, like brains or Eukaryotic cells, and digital systems. Most obviously, all such systems must finish their computation quickly, using as few degrees of freedom as possible. This means that they operate far from thermal equilibrium. Furthermore, many computers, both digital and biological, are modular, hierarchical systems with strong constraints on the connectivity among their subsystems. Yet another example is that to simplify their design, digital computers are required to be periodic processes governed by a global clock. None of these constraints were considered in 20th-century analyses of the thermodynamics of computation. The new field of stochastic thermodynamics provides formal tools for analyzing systems subject to all of these constraints. We argue here that these tools may help us understand at a far deeper level just how the fundamental thermodynamic properties of physical systems are related to the computation they perform.

Indexed as

computationenergy costsstochastic thermodynamics

Identifiers

PMID39471216
PMCPMC11551414

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.