Evidence map›Paper›PMID 39471210›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2024

Lateral cell polarization drives organization of epithelia in sea anemone embryos and embryonic cell aggregates.

Tavus Atajanova, Emily Minju Kang, Anna Postnikova, Alivia Lee Price, Sophia Doerr, Michael Du, Alicia Ugenti, Katerina Ragkousi

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. An abundant membrane protein in the NCAM superfamily is required for epithelial organization in sea anemone embryos.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Tavus Atajanova *Department of Biology, Amherst College, Amherst, MA 01002.ORCID 0009-0000-3811-778X
Emily Minju Kang *Department of Biology, Amherst College, Amherst, MA 01002.
Anna Postnikova *Department of Biology, Amherst College, Amherst, MA 01002.ORCID 0009-0005-2932-9365
Alivia Lee PriceDepartment of Biology, Amherst College, Amherst, MA 01002.
Sophia DoerrDepartment of Biology, Amherst College, Amherst, MA 01002.
Michael DuDepartment of Biology, Amherst College, Amherst, MA 01002.
Alicia UgentiDepartment of Biology, Amherst College, Amherst, MA 01002.
Katerina RagkousiDepartment of Biology, Amherst College, Amherst, MA 01002.ORCID 0000-0001-9383-225X

Funding

Cell cycle regulation of polarity proteins in proliferating epitheliaR15GM141979 · NIGMS · AMHERST COLLEGE · PI RAGKOUSI, KATERINA · 2021 to 2023
$553k
HHS | NIH | National Institute of General Medical Sciences (NIGMS) R15GM141979-01NIGMS NIH HHS R15 GM141979NSF (NSF) MRI-2117798
6 · The paper itself

Abstract

One of the first organizing processes during animal development is the assembly of embryonic cells into epithelia. Common features unite epithelialization across select bilaterians, however, we know less about the molecular and cellular mechanisms that drive epithelial emergence in early branching nonbilaterians. In sea anemones, epithelia emerge both during embryonic development and after cell aggregation of dissociated tissues. Although adhesion is required to keep cells together, it is not clear whether cell polarization plays a role as epithelia emerge from disordered aggregates. Here, we use the embryos of the sea anemone

Indexed as

Cell PolarityEmbryo, NonmammalianSea AnemonesAnimalsCell AggregationEmbryonic DevelopmentEpithelial CellsEpitheliumaggregateepithelialateral polaritylethal giant larvaeNematostella vectensis

Identifiers

PMID39471210
PMCPMC11573592

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.