ArticlePloS one2024
Mixed Leptospira infections in domestic animals from a rural community with high leptospirosis endemicity.
Article in PloS one, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Environmental Distribution of Pathogenic Leptospira spp. in Subtropical Rivers of Japan and Implications for Human Infection.Tropical medicine & international health : TM & IH · 2026Article
- Review
- High Positivity Rate forTropical medicine and infectious disease · 2026Article
- Molecular detection and phylogenetic characterization ofOpen veterinary journal · 2026Article
- Article
- Leptospira interrogans in the Galapagos sea lions (Zalophus wollebaeki).BMC zoology · 2025Article
- High prevalence and diversity ofOne health (Amsterdam, Netherlands) · 2025Article
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Authors and funding
7 authors.
Funding
Abstract
backgroundLeptospirosis is one of the most common zoonoses in the world which is associated with a severe febrile disease in humans causing a variety of syndromes including meningitis, interstitial nephritis, hepatitis, and sometimes death. Leptospirosis is caused by different pathogenic Leptospira species divided into almost 30 serogroups and more than 300 serovars which are carried by some animal asymptomatic chronic infections. Humans can become infected through direct contact with animal urine or indirectly by coming into contact with fresh water or mud contaminated with urine. METHODOLOGY/PRINCIPAL
findingsIn this research, we looked for leptospiral DNA in urine samples from dogs living in a rural, low-income and highly endemic community in the coast of Ecuador. We used molecular biology and next-generation sequencing for the detection. Our results showed evidence of two Leptospira species, L interrogans and L. santarosai, genomes in three dogs. CONCLUSIONS/SIGNIFICANCE: It has been widely known that animal carriers are typically infected with a single leptospiral strain. However, recent reports, including the present one, indicate that carrier animals may be coinfected with two or more leptospiral species.
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