Evidence map›Paper›PMID 39470938›Full record

Observational studyInternational urology and nephrology2025

A real-world evidence study of interhospital variability in the surgical treatment of patients with benign prostatic hyperplasia: the REVALURO study.

Povo Martín Iván, Budía Alba Alberto, Peri Cusí Lluís, D'Anna Maurizio, Gutiérrez Baños Jose Luís, Vicente Prados Francisco Javier, Sabio Bonilla Almudena, García Herrero Jaime, Torres Mingorance Esperanza, Bretos Azcona Pablo and 5 more

Abstract readObservational StudyMulticenter Study
In one paragraph

Observational study in International urology and nephrology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Povo Martín IvánConsorcio Hospital General Universitario, Av. de les Tres Creus, 2, Valencia, Spain.ORCID http://orcid.org/0000-0002-8680-942X
Budía Alba AlbertoHospital Universitario y Politécnico La Fe, Av. de Fernando Abril Martorell, 106, Valencia, Spain.ORCID http://orcid.org/0000-0002-9437-151X
Peri Cusí LluísHospital Clínic de Barcelona, C. de Villarroel, 170, Barcelona, Spain.ORCID http://orcid.org/0000-0001-5729-7034
D'Anna MaurizioHospital Clínic de Barcelona, C. de Villarroel, 170, Barcelona, Spain.ORCID http://orcid.org/0000-0002-1965-6961
Gutiérrez Baños Jose LuísHospital Universitario Marqués de Valdecilla, Av. De Valdecilla, Santander, Spain.ORCID http://orcid.org/0000-0002-6461-1172
Vicente Prados Francisco JavierHospital Universitario Virgen de las Nieves, Av. De las Fuerzas Armadas, 2, Granada, Spain.
Sabio Bonilla AlmudenaHospital Universitario Virgen de las Nieves, Av. De las Fuerzas Armadas, 2, Granada, Spain.ORCID http://orcid.org/0000-0003-4053-8238
García Herrero JaimeHospital Universitario Marqués de Valdecilla, Av. De Valdecilla, Santander, Spain.ORCID http://orcid.org/0009-0007-8948-7028
Torres Mingorance EsperanzaHealth Economics and Market Access, Boston Scientific Inc., Madrid, Spain.
Bretos Azcona PabloHealth Economics and Market Access, Boston Scientific Inc., Madrid, Spain.ORCID http://orcid.org/0000-0001-8209-1038
Ojeda Arqueros GabrielaHealth Outcomes Performance Ecosystem for Sustainability (HOPES), Valencia, Spain.ORCID http://orcid.org/0009-0003-3152-0199
Gómez-Barrera ManuelPharmacoeconomics and Outcomes Research Iberia (PORIB), Paseo Joaquín Rodrigo 4 - Letter I, Madrid, Spain.ORCID http://orcid.org/0000-0001-8357-1279
Casado Miguel ÁngelPharmacoeconomics and Outcomes Research Iberia (PORIB), Paseo Joaquín Rodrigo 4 - Letter I, Madrid, Spain.ORCID http://orcid.org/0000-0002-8743-6653
de la Cuadra-Grande AlbertoPharmacoeconomics and Outcomes Research Iberia (PORIB), Paseo Joaquín Rodrigo 4 - Letter I, Madrid, Spain. adelacuadra@porib.com.ORCID http://orcid.org/0000-0002-2501-3049
López Alcina EmilioConsorcio Hospital General Universitario, Av. de les Tres Creus, 2, Valencia, Spain.ORCID http://orcid.org/0000-0002-7377-6331

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeLower urinary tract symptoms associated with benign prostatic hyperplasia (LUTS/BPH) is a growing condition in males associated with a high clinical, economic and humanistic burden. Several surgical techniques are available for the treatment of LUTS/BPH; thus, the aim of this study was to describe and explore the variability in the use of surgical procedures among Spanish hospitals.

methodsThe REVALURO was a retrospective, observational study conducted by collecting data from the clinical records of patients with LUTS/BPH aged ≥ 35 years, from 5 national reference hospitals, who were surgically treated between 2018 and 2022.

resultsAmong the 3038 patients who underwent 3084 surgeries, 66% were invasive (2018: 57.5%, 2022: 71.5%), 22% were minimally invasive (MISTs) (2018: 20.7%, 2022: 20.2%) and 12% were highly invasive (2018: 21.8%, 2022: 8.4%). A total of 22.4% of patients' complications, with a maximum incidence of 28.6% (open prostatectomy) and a minimum 0.8% (water vapor thermal therapy (WVTT)] (p < 0.001). The reintervention rate was 1.5% over the study period. The median length of hospital stay after surgery increased from 0 days (interquartile range [IQR]: 0) with WVTT to 5 days (IQR: 4-8) with open prostatectomy (p < 0.001).

conclusionTrends in surgical treatment showed that the use of invasive techniques increased, while the use of highly invasive techniques decreased, and the use of MISTs remained constant. However, given the heterogeneity among hospitals, national clinical guidelines and recommendations are needed to guide the decision on which technique should be used and to homogenize the criteria.

Indexed as

ProstatectomyProstatic HyperplasiaAdultAgedHumansMaleMiddle AgedMinimally Invasive Surgical ProceduresRetrospective StudiesSpainBenign prostatic hyperplasiaLower urinary tract symptomsReal-world dataReal-world evidenceSurgical treatment

Identifiers

PMID39470938
PMCPMC11821794

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.