Evidence map›Paper›PMID 39470937›Full record

ArticleEJNMMI radiopharmacy and chemistry2024

Design and development of nanoprobes radiolabelled with

María Jimena Salgueiro, Mariano Portillo, Fiorella Tesán, Melisa Nicoud, Vanina Medina, Marcela Moretton, Diego Chiappetta, Marcela Zubillaga

Abstract read
In one paragraph

Article in EJNMMI radiopharmacy and chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. SoluplusInternational journal of molecular sciences · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

María Jimena SalgueiroCátedra de Física, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Junín 956 PB , Buenos Aires (1113), Argentina. jsalgueiro@ffyb.uba.ar.
Mariano PortilloCátedra de Física, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Junín 956 PB , Buenos Aires (1113), Argentina.
Fiorella TesánCátedra de Física, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Junín 956 PB , Buenos Aires (1113), Argentina.
Melisa NicoudLaboratory of Tumor Biology and Inflammation, Biomedical Research Institute (BIOMED), Faculty of Medical Sciences, Pontifical Catholic University of Argentina, (UCA-CONICET), Buenos Aires, Argentina.
Vanina MedinaLaboratory of Tumor Biology and Inflammation, Biomedical Research Institute (BIOMED), Faculty of Medical Sciences, Pontifical Catholic University of Argentina, (UCA-CONICET), Buenos Aires, Argentina.
Marcela MorettonInstituto de Tecnología Farmacéutica y Biofarmacia (InTecFyB), Universidad de Buenos Aires, Buenos Aires, Argentina.
Diego ChiappettaInstituto de Tecnología Farmacéutica y Biofarmacia (InTecFyB), Universidad de Buenos Aires, Buenos Aires, Argentina.
Marcela ZubillagaCátedra de Física, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Junín 956 PB , Buenos Aires (1113), Argentina.ORCID http://orcid.org/0000-0002-7331-6722

Funding

Secretaria de Ciencia y Tecnica, Universidad de Buenos Aires 20020220300178BA
6 · The paper itself

Abstract

backgroundPrevious studies employing polymeric micelles and molecular imaging for in vivo nanosystem characterization have led to the development of radionanoprobes (RNPs) designed for diagnosing and monitoring therapeutic interventions in preclinical oncology research, specifically within breast and colon cancer models. These models exhibit high GLUT1 expression on tumor cells and VEGFR expression on the tumor vasculature. We aimed to enhance the tumor-targeting specificity of these RNPs by functionalizing micelles with glucose and bevacizumab. The choice of

resultsFour RNPs ([

conclusionsSoluplus

Indexed as

99mTcMicellesMolecular imagingOncology

Identifiers

PMID39470937
PMCPMC11522242

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.