Evidence map›Paper›PMID 39470900›Full record

ArticleEndocrine2025

Autoimmune thyroiditis incidence in a large population-based study in northeastern Italy.

Simona Censi, Laura Salmaso, Filippo Ceccato, Fiammetta Battheu, Cristina Clausi, Ilaria Piva, Ugo Fedeli, Loris Bertazza, Susi Barollo, Mario Saia and 1 more

Abstract read
PubMed Publisher
In one paragraph

Article in Endocrine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Simona CensiEndocrinology Unit, Department of Medicine (DIMED), University of Padua, Padua, Italy.
Laura SalmasoClinical Governance Unit, Azienda Zero Regione Veneto, Padua, Italy.
Filippo CeccatoEndocrinology Unit, Department of Medicine (DIMED), University of Padua, Padua, Italy.
Fiammetta BattheuEndocrinology Unit, Department of Medicine (DIMED), University of Padua, Padua, Italy.
Cristina ClausiEndocrinology Unit, Department of Medicine (DIMED), University of Padua, Padua, Italy.
Ilaria PivaEndocrinology Unit, Department of Medicine (DIMED), University of Padua, Padua, Italy.
Ugo FedeliClinical Governance Unit, Azienda Zero Regione Veneto, Padua, Italy.
Loris BertazzaEndocrinology Unit, Department of Medicine (DIMED), University of Padua, Padua, Italy.
Susi BarolloEndocrinology Unit, Department of Medicine (DIMED), University of Padua, Padua, Italy.
Mario SaiaClinical Governance Unit, Azienda Zero Regione Veneto, Padua, Italy.
Caterina MianEndocrinology Unit, Department of Medicine (DIMED), University of Padua, Padua, Italy. caterina.mian@unipd.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeAn improvement in iodine status in the Veneto region (Italy) in the last decade has been documented. Our aim was to estimate the incidence of autoimmune thyroiditis (AT) in this region over the period 2012-2022.

methodsA retrospective population-based study conducted in Veneto using the population registry and administrative health databases. We documented incident hyperthyroidism from 2013 to 2022 to exclude prevalent cases and calculated standardised incidence rates (IR) per 10,000 person-years by age and sex.

resultsWe identified 65,379 incident cases (IR: 13.38), 5.44-fold higher in females than in males. IR decreased from 15.86 (95% CI: 15.50, 16.21) in 2013 to 12.35 (95% CI: 12.04, 12.67) in 2022. The decline was evident only in females, with a documented reduction in IR from 27.26 (95% CI: 26.61, 27.91) in 2013 to 20.49 (95% CI: 19.92, 21.07) in 2022 (P = 0.002). The decrease was sharper in females aged 15-54 years (IR from 37.86 (95%CI: 36.79, 38.94) in 2013 to 27.40 (95% CI: 26.44, 28.36) in 2022; P < 0.001) than in those aged ≥55 years (IR from 20.06 (95% CI: 19.13, 20.99) in 2013 to 16.56 (95% CI: 15.78, 17.35) in 2022; P = 0.034). In 2020, an out-of-trend decrease in AT incidence was documented, corresponding with the SARS-CoV-2 pandemic, with a realignment to the trend in the subsequent years.

conclusionsA decline in AT was documented in the Veneto region in the last decade, paralleling improvement in the iodine status. The reduction was significant only among females, particularly in reproductive age.

Indexed as

Thyroiditis, AutoimmuneAdolescentAdultAgedAged, 80 and overChildFemaleHumansIncidenceItalyMaleMiddle AgedRegistriesRetrospective StudiesYoung AdultIncidenceIodineThyroiditis

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.