Evidence map›Paper›PMID 39470776›Full record

ArticleAnnals of hematology2024

Clinical characteristics and prognostic analysis of pediatric hemophagocytic lymphohistiocytosis using lasso-logistic regression.

Nandu Luo, Guangli Yang, Baoli Li, Pingping Zhang, Jinhua Ma, Yan Chen, Zuochen Du, Pei Huang

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Article in Annals of hematology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Nandu LuoDepartment of Pediatrics, Affiliated Hospital of Zunyi Medical University, Zunyi, China.
Guangli YangDepartment of Pediatrics, Affiliated Hospital of Zunyi Medical University, Zunyi, China.
Baoli LiDepartment of Pediatrics, Affiliated Hospital of Zunyi Medical University, Zunyi, China.
Pingping ZhangDepartment of Pediatrics, Affiliated Hospital of Zunyi Medical University, Zunyi, China.
Jinhua MaDepartment of Pediatrics, Affiliated Hospital of Zunyi Medical University, Zunyi, China.
Yan ChenDepartment of Pediatrics, Affiliated Hospital of Zunyi Medical University, Zunyi, China.
Zuochen DuDepartment of Pediatrics, Affiliated Hospital of Zunyi Medical University, Zunyi, China. dzc9036@126.com.
Pei HuangDepartment of Pediatrics, Affiliated Hospital of Zunyi Medical University, Zunyi, China. fenglin4620@163.com.

Funding

Guizhou Provincial Science and Technology Project QKHCG[2024]ZD012Guizhou Provincial Science and Technology Project QKHZK-2022-YB641Zunyi Municipal Science and Technology Project ZSKRPT-2023-6
6 · The paper itself

Abstract

This study aims to evaluate and predict mortality risks among pediatric patients with hemophagocytic lymphohistiocytosis (HLH). We conducted a retrospective analysis of pediatric patients with HLH diagnosed at the Affiliated Hospital of Zunyi Medical University between January 2012 and April 2023. Patients were divided into a death group and a survival group based on their outcomes. Risk factors for mortality were analyzed using a lasso-logistic regression model. This study included 142 pediatric patients with HLH, with a median age of 40.5 (14.75-84) months, of whom 78 (54.93%) were male. The overall mortality rate was 34.51%. Through lasso-logistic regression analysis, five independent prognostic factors were identified: concurrent central nervous system involvement, multiple organ dysfunction syndrome involving three or more organs, platelet count ≤ 42.5 × 10

Indexed as

Lymphohistiocytosis, HemophagocyticChildChild, PreschoolFemaleHumansInfantLogistic ModelsMaleMultiple Organ FailurePrognosisRetrospective StudiesRisk FactorsSurvival RateBlood purificationChildrenHemophagocytic lymphohistiocytosisLassoPrognostic factors

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.